Intermediates

4-Phenylbutan-2-amine

  • CAS No.22374-89-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Phenylbutan-2-amine (CAS 22374-89-6) designed for pharmaceutical synthesis, specifically as a key intermediate for Labetalol production with guaranteed quality.

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Product Technical Details

Product Overview

4-Phenylbutan-2-amine is a high-value organic intermediate extensively utilized in the pharmaceutical industry for the synthesis of complex therapeutic agents. As a critical building block, this compound serves as a foundational precursor in the manufacturing of Labetalol, a widely prescribed antihypertensive medication. Our facility specializes in the production of this amine derivative with stringent quality controls to ensure consistency and reliability for downstream pharmaceutical applications.

We understand the importance of purity and structural integrity in medicinal chemistry. Therefore, our manufacturing process adheres to rigorous industrial standards, delivering a product that meets the exacting requirements of modern drug synthesis. This chemical is supplied as a colorless liquid, optimized for ease of handling and integration into various organic reaction pathways.

Technical Specifications

The following table outlines the key physical and chemical properties of our 4-Phenylbutan-2-amine. These parameters are verified through advanced analytical methods to guarantee compliance with specified standards.

ParameterValue
CAS Number22374-89-6
Molecular FormulaC10H15N
Molecular Weight149.233 g/mol
AppearanceColorless liquid
Assay (GC)≥99.0%
Assay (Titration)≥99.0%
Moisture Content≤0.5%
Boiling Point221.5±0.0 °C at 760 mmHg
Density0.9±0.1 g/cm3
Flash Point97.8±0.0 °C

Industrial Applications

The primary application of 4-Phenylbutan-2-amine lies in the pharmaceutical sector, specifically as an intermediate for Labetalol synthesis. Labetalol is a crucial medication used to manage high blood pressure and certain heart conditions. The quality of the intermediate directly impacts the efficacy and safety of the final active pharmaceutical ingredient (API). Our product ensures optimal reaction yields and minimizes impurity profiles during the synthesis process.

Beyond Labetalol, this amine derivative serves as a versatile building block in organic chemistry. It is suitable for research and development projects focused on novel cardiovascular therapeutics and other neurological applications. The high purity level facilitates cleaner reactions, reducing the need for extensive purification steps in subsequent manufacturing stages.

Quality Assurance and Safety

Quality is the cornerstone of our operation. Every batch of 4-Phenylbutan-2-amine undergoes comprehensive testing using gas chromatography and titration methods. We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for purity, moisture, and physical constants. Our production facilities operate under strict safety protocols to ensure environmental compliance and worker safety.

  • Consistent batch-to-batch reproducibility
  • Advanced impurity profiling and control
  • Compliance with international chemical safety standards
  • Full traceability from raw materials to finished goods

Packaging and Logistics

To maintain product integrity during transit, 4-Phenylbutan-2-amine is packaged in secure 200 kg drums. Custom packaging solutions are available upon request to meet specific logistical requirements. We recommend storing the chemical in a cool, ventilated area away from direct sunlight and incompatible substances. Our global logistics network ensures timely delivery to manufacturers and research institutions worldwide, supported by comprehensive technical documentation and regulatory assistance.