4-Piperidin-4-ylmorpholine
- CAS No.53617-35-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Piperidin-4-ylmorpholine (CAS 53617-35-9) serves as a critical pharmaceutical intermediate for Alectinib synthesis, available in bulk quantities.
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Product Overview
4-Piperidin-4-ylmorpholine is a sophisticated heterocyclic organic compound widely recognized for its pivotal role in modern medicinal chemistry. As a key structural building block, this chemical facilitates the synthesis of complex pharmaceutical agents, specifically serving as an essential intermediate in the production of Alectinib (AF802). Our facility specializes in the large-scale manufacturing of this high-value compound, ensuring consistent quality and reliability for global research and development teams.
The molecular architecture combines a piperidine ring with a morpholine moiety, creating a versatile scaffold that enhances solubility and bioavailability in downstream drug candidates. We adhere to strict production protocols to maintain the integrity of the chemical structure, delivering material that meets rigorous industry standards for purity and performance.
Technical Specifications
Quality control is paramount in our manufacturing process. Each batch undergoes comprehensive analytical testing to verify compliance with specified parameters. The following table outlines the standard technical specifications for our commercial grade 4-Piperidin-4-ylmorpholine:
| Parameter | Specification |
|---|---|
| CAS Number | 53617-35-9 |
| Molecular Formula | C9H20Cl2N2O |
| Molecular Weight | 243.17 g/mol |
| Appearance | White to light yellow solid |
| Purity (GC) | ≥98.0% |
| Melting Point | 40-43°C |
| Boiling Point | 256.3°C |
| Flash Point | 108.8°C |
| Density | 1.033 g/cm3 |
Primary Applications
The primary application of this compound lies within the pharmaceutical sector, specifically as a precursor for kinase inhibitors. It is extensively utilized in the synthesis pathway of Alectinib, a targeted therapy used in the treatment of non-small cell lung cancer. Researchers and process chemists value this intermediate for its reactivity and stability during multi-step organic synthesis routes.
Beyond oncology, the piperidinyl-morpholine scaffold is investigated for various neurological and therapeutic applications due to its ability to interact with specific biological receptors. Our product supports both pilot-scale research and full-scale commercial manufacturing, providing a reliable supply chain for drug development projects.
Quality Assurance and Packaging
We implement a robust quality management system to ensure every shipment meets the declared specifications. Certificates of Analysis (COA) are provided with each order, detailing batch-specific test results including purity profiles and impurity limits. Our commitment to transparency allows clients to validate material quality before integration into their processes.
Standard packaging consists of 25 kg drums, designed to protect the product from moisture and contamination during transit. However, we understand that diverse projects have unique requirements. Therefore, we offer custom packaging solutions tailored to specific client needs, ensuring safe handling and storage regardless of order volume.
Storage and Safety Handling
To maintain optimal stability, 4-Piperidin-4-ylmorpholine should be stored in a cool, ventilated environment away from direct sunlight and heat sources. Containers must remain tightly sealed when not in use to prevent absorption of atmospheric moisture. Proper personal protective equipment (PPE) is recommended during handling to ensure safety in laboratory or industrial settings.
Our logistics network supports global shipping, complying with all relevant international transportation regulations for chemical goods. We prioritize timely delivery while maintaining the integrity of the product throughout the supply chain. For detailed safety data sheets (SDS) or technical inquiries, our support team is available to assist with comprehensive documentation and guidance.
