Intermediates

4-Pyridin-4-yl-3H-1,3-thiazole-2-thione

  • CAS No.77168-63-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used primarily in the synthesis of advanced cephalosporin antibiotics. Available in bulk quantities with full documentation.

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Product Technical Details

Product Overview

4-Pyridin-4-yl-3H-1,3-thiazole-2-thione is a sophisticated heterocyclic compound that serves as a critical building block in modern medicinal chemistry. Our facility specializes in the production of this high-value intermediate, ensuring consistent quality and reliability for pharmaceutical manufacturing partners. The compound features a unique thiazole ring structure substituted with a pyridine moiety, offering specific reactivity profiles essential for complex organic synthesis.

We understand the stringent requirements of the pharmaceutical industry. Therefore, our manufacturing process is designed to maximize yield while minimizing impurities. Each batch is subjected to rigorous analytical testing to confirm identity and purity levels. This commitment to excellence makes our product a preferred choice for researchers and production facilities focused on developing advanced therapeutic agents.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates. We adhere to strict internal standards that often exceed general industry expectations. The physical and chemical properties are carefully monitored to ensure compatibility with downstream synthesis processes. Below are the key specifications for our standard commercial grade material.

Parameter Value
CAS Number 77168-63-9
Molecular Formula C8H6N2S2
Molecular Weight 194.28 g/mol
Appearance Off-white to light yellow powder
Purity ≥98.5%
Loss on Drying ≤0.5%
Total Impurities ≤1.0%
Largest Single Impurity ≤0.5%

Industrial Applications

This thiazole derivative is primarily utilized in the pharmaceutical sector as a key intermediate. Its most notable application is in the synthesis of ceftaroline, a fifth-generation cephalosporin antibiotic. The specific structural arrangement of the pyridine and thiazole rings allows for precise coupling reactions required in the assembly of beta-lactam antibiotics. Beyond this specific use, the compound serves as a versatile precursor in the development of other heterocyclic pharmaceuticals.

Chemists value this material for its stability and reactivity balance. It facilitates the construction of complex molecular architectures needed for next-generation medicines. Our supply chain supports both research-scale quantities and large-scale commercial production, ensuring continuity for your development pipelines.

Storage and Handling

Proper storage is critical to maintain the integrity of this chemical intermediate. The product should be stored in a cool, ventilated place away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent contamination or degradation. We recommend storing the material in its original packaging until ready for use.

When handling this compound, standard laboratory safety protocols should be followed. Personnel should wear appropriate personal protective equipment, including gloves and safety goggles. Adequate ventilation is necessary to avoid inhalation of dust. In case of spillage, standard chemical cleanup procedures should be implemented immediately to ensure workplace safety.

Quality Assurance

Every shipment is accompanied by a Certificate of Analysis (COA) detailing the test results for that specific batch. Our quality assurance team conducts multiple checks throughout the production cycle. We are committed to providing transparent documentation and reliable support to our global clientele. For custom packaging requirements or specific purity grades, please contact our sales team for further discussion.