Intermediates

4-Sulfonamide-phenylhydrazine Hydrochloride

  • CAS No.27918-19-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Sulfonamide-phenylhydrazine Hydrochloride (CAS 27918-19-0) designed for pharmaceutical synthesis. Reliable supply for Celecoxib intermediate production with strict quality control.

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Product Technical Details

Product Overview

4-Sulfonamide-phenylhydrazine Hydrochloride is a critical organic intermediate widely utilized in the pharmaceutical and fine chemical industries. This compound serves as a fundamental building block in the synthesis of complex heterocyclic structures, particularly within the realm of non-steroidal anti-inflammatory drug (NSAID) development. Our manufacturing process ensures exceptional stability and reactivity, making it an ideal candidate for large-scale industrial applications. The hydrochloride salt form enhances solubility and handling characteristics during various synthetic transformations.

As a dedicated chemical manufacturer, we prioritize consistency and reliability. Each batch undergoes rigorous analytical testing to confirm identity and purity levels. This commitment to quality supports downstream processors in achieving high yields and minimizing impurities in final active pharmaceutical ingredients. Our facility adheres to strict international standards, ensuring that every kilogram supplied meets the demanding requirements of modern medicinal chemistry.

Technical Specifications

Precise physical and chemical properties are essential for reproducible synthesis outcomes. The following table outlines the key parameters verified through our quality control laboratories. We employ advanced chromatographic and spectroscopic methods to validate these specifications against established benchmarks.

ParameterValue
CAS Number27918-19-0
Molecular FormulaC6H9N3O2S
Molecular Weight187.220
AppearanceOff-white to yellow or orange crystalline powder
Assay (HPLC)≥98.0%
Melting Point180°C
Density1.5±0.1 g/cm3
Boiling Point434.7±47.0 °C at 760 mmHg

Industrial Applications

The primary application of this intermediate lies in the production of Celecoxib, a well-known therapeutic agent. Its specific structural configuration allows for efficient coupling reactions necessary for constructing the target molecule. Beyond this specific pathway, 4-Sulfonamide-phenylhydrazine Hydrochloride is valuable in research and development settings exploring new sulfonamide derivatives. Chemists utilize this reagent to investigate structure-activity relationships and develop novel pharmacological candidates.

  • Key precursor in Celecoxib synthesis pathways
  • Utilized in medicinal chemistry R&D programs
  • Suitable for scalable industrial manufacturing processes
  • Compatible with various organic synthesis protocols

Quality Assurance And Logistics

We understand that supply chain integrity is as vital as product quality. Our packaging options include standard 25 kg drums, with customization available to meet specific client logistical needs. Proper storage is maintained in cool, ventilated environments to preserve chemical integrity over extended periods. Every shipment is accompanied by a comprehensive Certificate of Analysis (COA), providing full transparency on test results. Our global distribution network ensures timely delivery while maintaining compliance with international shipping regulations for chemical goods.