Intermediates

4-(Trifluoromethoxy)benzenesulfonamide

  • CAS No.1513-45-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity fluorinated intermediate for advanced organic synthesis and pharmaceutical research applications.

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Product Technical Details

Product Overview

4-(Trifluoromethoxy)benzenesulfonamide is a highly specialized fluorinated organic intermediate designed for advanced chemical synthesis applications. This compound features a unique trifluoromethoxy substituent on the benzene ring, which significantly enhances the lipophilicity and metabolic stability of downstream molecules. As a critical building block, it is extensively utilized in the development of pharmaceutical agents, agrochemical formulations, and functional materials. Our manufacturing process ensures consistent quality and high purity levels suitable for rigorous research and industrial scale production.

The introduction of the trifluoromethoxy group is a strategic modification in medicinal chemistry, often employed to improve membrane permeability and binding affinity. This sulfonamide derivative serves as a versatile precursor for various coupling reactions, including nucleophilic substitutions and cross-coupling protocols. We maintain strict quality control standards throughout production to guarantee that every batch meets the specified physicochemical properties required by our global clientele.

Technical Specifications

ParameterValue
CAS Number1513-45-7
Molecular FormulaC7H6F3NO3S
Molecular Weight241.19 g/mol
AppearanceWhite Solid
Assay (Purity)≥98.0%
Melting Point146-148°C
Moisture Content≤0.2%
Density1.519 g/cm3
Boiling Point301.8°C

Industrial Applications

This fluorinated intermediate is primarily employed in the synthesis of complex organic molecules where enhanced biological activity is required. The sulfonamide moiety provides a robust framework for further functionalization, making it an ideal candidate for drug discovery pipelines. Researchers utilize this compound to explore structure-activity relationships (SAR) in novel therapeutic candidates. Additionally, it finds application in the agrochemical sector for developing next-generation pesticides and herbicides with improved environmental profiles.

  • Pharmaceutical intermediate for API synthesis
  • Agrochemical research and development
  • Material science and polymer modification
  • Custom organic synthesis projects

Quality Assurance and Storage

We adhere to international quality management systems to ensure product reliability. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing batch-specific test results. Proper storage is essential to maintain the integrity of the chemical. The product should be kept in a cool, ventilated area away from direct sunlight and moisture. Containers must be tightly sealed when not in use to prevent contamination or degradation. Our logistics team ensures safe packaging using 25 kg drums or customized solutions based on customer requirements.

For large-scale procurement or technical inquiries regarding synthesis routes, our expert support team is available to provide detailed documentation and regulatory guidance. We are committed to supplying high-performance chemical solutions that drive innovation in the pharmaceutical and chemical industries. Our commitment to safety and compliance ensures that all materials are handled according to standard operating procedures for hazardous chemicals.