4-(Trifluoromethoxy)benzoic acid
- CAS No.330-12-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-(Trifluoromethoxy)benzoic acid (CAS 330-12-1), a key fluorinated aromatic intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
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Product Overview
4-(Trifluoromethoxy)benzoic acid is a high-value fluorinated aromatic carboxylic acid widely employed as a critical building block in modern organic synthesis. With its electron-withdrawing trifluoromethoxy group positioned para to the carboxylic acid functionality, this compound exhibits enhanced stability and unique reactivity profiles, making it indispensable in the development of complex pharmaceutical APIs, agrochemicals, and specialty materials.
Specifications
| Molecular Formula | C8H5F3O3 |
|---|---|
| Molecular Weight | 206.12 g/mol |
| Appearance | White powder |
| Assay | ≥99.0% |
| Moisture | ≤0.2% |
| Melting Point | 150–154°C |
| Boiling Point | 230.2°C |
| Density | 1.447 g/cm³ |
| Flash Point | 93°C |
| Refractive Index | 1.478 |
Industrial Applications
As a versatile fluoroaromatic intermediate, 4-(Trifluoromethoxy)benzoic acid serves as a foundational scaffold in multi-step syntheses requiring robust metabolic stability and lipophilicity modulation. Its primary applications include:
- Pharmaceutical research: Synthesis of bioactive molecules targeting neurological therapeutics and anti-inflammatory agents.
- Agrochemical innovation: Construction of novel herbicides and fungicides with improved environmental persistence profiles.
- Materials science: Precursor for liquid crystals and high-performance polymers requiring thermal and chemical resistance.
Manufactured under stringent quality control protocols, our product meets global regulatory standards for industrial-scale chemical production. Packaging is typically provided in 25 kg drums, with custom configurations available upon request. Store in a cool, dry, and well-ventilated area away from incompatible substances.
