4-(Trifluoromethoxy)benzoyl Chloride
- CAS No.36823-88-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-(Trifluoromethoxy)benzoyl Chloride is a key fluorinated intermediate for pharmaceutical and agrochemical synthesis. We offer reliable supply with strict quality control.
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Product Overview
4-(Trifluoromethoxy)benzoyl Chloride is a specialized fluorinated organic intermediate widely utilized in the synthesis of complex pharmaceutical compounds and advanced agrochemical formulations. As a derivative of benzoic acid featuring a trifluoromethoxy substituent, this compound offers enhanced lipophilicity and metabolic stability when incorporated into final active ingredients. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications.
The introduction of the trifluoromethoxy group is a strategic modification in medicinal chemistry, often employed to improve the bioavailability and binding affinity of drug candidates. This acyl chloride serves as a versatile building block, enabling chemists to construct diverse molecular architectures through nucleophilic substitution reactions. We are committed to supplying this critical reagent with full traceability and comprehensive documentation.
Technical Specifications
Our production facility adheres to strict quality management systems to guarantee that every batch meets or exceeds industry standards. The physical and chemical properties are rigorously tested using advanced analytical instrumentation. Below are the typical specifications for our commercial grade product:
| Parameter | Specification |
|---|---|
| CAS Number | 36823-88-8 |
| Molecular Formula | C8H4ClF3O2 |
| Molecular Weight | 224.56 g/mol |
| Appearance | Colorless transparent liquid |
| Assay (Purity) | ≥98.0% |
| Moisture Content | ≤0.2% |
| Density | 1.425 g/cm3 |
| Boiling Point | 55-56°C |
| Refractive Index | 1.472 |
Industrial Applications
This fluorinated intermediate is primarily employed in the organic synthesis sector, serving as a precursor for various high-value chemicals. In the pharmaceutical industry, it is used to develop novel therapeutic agents where metabolic stability is crucial. The electron-withdrawing nature of the trifluoromethoxy group influences the reactivity of the carbonyl carbon, making it an excellent electrophile for amidation and esterification processes.
Additionally, this compound finds applications in the agrochemical sector for the production of herbicides and pesticides. Its stability under various environmental conditions makes it a preferred choice for formulators seeking durable active ingredients. Researchers also utilize this building block in the development of specialty materials and fine chemicals where specific fluorine placement is required for performance optimization.
Quality Assurance And Storage
We understand the importance of material integrity in chemical synthesis. Each production batch undergoes comprehensive testing, including gas chromatography and moisture analysis, to confirm compliance with specifications. A Certificate of Analysis (COA) is provided with every shipment to ensure transparency and quality verification. Our logistics team ensures secure packaging to prevent degradation during transit.
For optimal storage, the product should be kept in a cool, ventilated area away from direct sunlight and moisture sources. The standard packaging option is 200 kg per drum, though we offer flexible customization to meet specific client requirements. Proper handling procedures should be followed to maintain safety and product quality throughout the supply chain. Contact our sales team for detailed safety data sheets and bulk pricing information.
