Intermediates

4-(Trifluoromethoxy)benzyl chloride

  • CAS No.65796-00-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 4-(Trifluoromethoxy)benzyl chloride designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

4-(Trifluoromethoxy)benzyl chloride is a highly specialized fluorinated building block essential for modern medicinal chemistry and agrochemical development. As a key intermediate, this compound facilitates the introduction of the trifluoromethoxy group into complex molecular structures, enhancing metabolic stability and lipophilicity in final active pharmaceutical ingredients. Our manufacturing process ensures exceptional consistency and purity, meeting the rigorous demands of global research and production facilities.

Key Specifications

ParameterValue
CAS Number65796-00-1
Molecular FormulaC8H6ClF3O
Molecular Weight210.58 g/mol
AppearanceColorless clear liquid
Purity (GC)≥99.0%
Density1.34 g/cm3
Boiling Point72oC
Flash Point61oC
Refractive Index1.415

Industrial Applications

This benzyl chloride derivative serves as a versatile reagent in nucleophilic substitution reactions. It is predominantly utilized in the synthesis of pharmaceutical APIs where fluorine substitution is required to improve bioavailability. Additionally, it finds application in the production of advanced polymers and specialty materials. The trifluoromethoxy moiety provides unique electronic properties that are valuable in designing next-generation therapeutic agents.

Quality Assurance

We adhere to strict quality control protocols to guarantee product integrity. Every batch undergoes comprehensive analysis using Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR) spectroscopy. Certificate of Analysis (COA) documents are provided with each shipment, detailing specific test results against our internal specifications. Our facility maintains ISO compliant standards to ensure safety and reliability throughout the manufacturing process.

Storage and Handling

To maintain stability, store this product in a cool, ventilated area away from direct sunlight and moisture. Keep containers tightly closed when not in use. Due to its reactive nature as an alkyl halide, appropriate personal protective equipment (PPE) should be worn during handling. Avoid contact with strong oxidizing agents and bases. In case of spillage, follow standard chemical safety procedures for containment and disposal.

Packaging and Logistics

Standard packaging consists of 200 kg drums, ensuring safe transport for bulk orders. We also offer customized packaging solutions to meet specific client requirements. Our global logistics network supports timely delivery to major industrial hubs worldwide. For technical support, sample requests, or bulk pricing inquiries, please contact our sales team directly.