4-(Trifluoromethoxy)chlorobenzene
- CAS No.461-81-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-(Trifluoromethoxy)chlorobenzene (CAS 461-81-4) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical intermediates.
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Product Overview
4-(Trifluoromethoxy)chlorobenzene is a specialized fluorinated aromatic compound widely recognized for its stability and reactivity in complex organic synthesis pathways. As a critical building block, this chemical intermediate facilitates the introduction of trifluoromethoxy groups into molecular structures, enhancing lipophilicity and metabolic stability in downstream applications. Our manufacturing process ensures consistent quality, making it an ideal choice for research laboratories and industrial production facilities requiring precise chemical specifications.
We understand the demands of modern chemical synthesis, where purity and reliability are paramount. This product undergoes rigorous quality control testing at every stage of production. From raw material sourcing to final packaging, we maintain strict adherence to international standards to guarantee that every batch meets the specified assay requirements. Our commitment to excellence supports our partners in achieving successful outcomes in their respective synthesis projects.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 461-81-4 |
| Molecular Formula | C7H4ClF3O |
| Molecular Weight | 196.554 |
| Appearance | White to light yellow powder |
| Assay | ≥98.0% |
| Melting Point | 51-53 °C |
| Boiling Point | 145.9±35.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 42.0±25.9 °C |
| Refractive Index | 1.452 |
Key Advantages
- High Chemical Purity: Ensures minimal impurities for sensitive reaction pathways.
- Consistent Quality: Batch-to-batch reproducibility for large-scale manufacturing.
- Global Supply Chain: Reliable logistics and timely delivery worldwide.
- Technical Support: Expert assistance for application-specific inquiries.
- Flexible Packaging: Customizable options to suit production needs.
Applications and Usage
This fluorinated intermediate serves as a versatile precursor in the synthesis of various high-value compounds. It is extensively utilized in the pharmaceutical industry for developing novel therapeutic agents where metabolic stability is crucial. Additionally, it finds application in agrochemical synthesis, contributing to the creation of effective crop protection solutions. The trifluoromethoxy group imparts unique electronic and steric properties, making this compound invaluable for medicinal chemistry and material science research.
Researchers and process chemists value this material for its predictable reactivity profile. Whether used in cross-coupling reactions or nucleophilic substitutions, 4-(Trifluoromethoxy)chlorobenzene provides a reliable foundation for constructing complex molecular architectures. Our team works closely with clients to understand their specific formulation requirements, ensuring the product aligns perfectly with their process parameters.
Storage and Safety
Proper storage is essential to maintain the integrity of this chemical product. It should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent contamination or degradation. We recommend following standard laboratory safety protocols when handling this material, including the use of appropriate personal protective equipment. For detailed safety information, please refer to the provided Safety Data Sheet (SDS) accompanying each shipment.
