4-(Trifluoromethoxy)phenyl Isocyanate
- CAS No.35037-73-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-(Trifluoromethoxy)phenyl Isocyanate (CAS 35037-73-1) designed for advanced organic synthesis and pharmaceutical intermediate manufacturing.
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Product Overview
4-(Trifluoromethoxy)phenyl Isocyanate represents a critical fluorinated building block within the realm of advanced organic chemistry and industrial manufacturing. As a specialized aryl isocyanate derivative, this compound is engineered to facilitate complex molecular constructions required in modern pharmaceutical and agrochemical development pipelines. The incorporation of the trifluoromethoxy group significantly enhances the lipophilicity and metabolic stability of downstream molecules, making it an indispensable reagent for medicinal chemists aiming to optimize drug candidates. Our manufacturing process ensures consistent quality and high reactivity, supporting diverse synthetic pathways for global clients.
Key Specifications and Physical Properties
We maintain rigorous quality control standards to guarantee that every batch meets international specifications for fine chemicals. The following table outlines the fundamental physical and chemical characteristics of this material. These parameters are essential for process engineers when designing reaction conditions, safety protocols, and storage requirements for large-scale operations.
| Parameter | Value |
|---|---|
| CAS Number | 35037-73-1 |
| Molecular Formula | C8H4F3NO2 |
| Molecular Weight | 203.118 g/mol |
| Appearance | Light yellow liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 181.8±40.0 °C at 760 mmHg |
| Melting Point | -29°C |
| Flash Point | 70.0±0.0 °C |
| Refractive Index | 1.457 |
Industrial Applications and Utility
This fluorinated isocyanate serves primarily as a versatile intermediate in organic synthesis and chemical manufacturing. Its primary utility lies in the formation of urea and carbamate linkages, which are prevalent structures in bioactive molecules and functional materials. Researchers utilize this compound to introduce fluorine atoms into aromatic systems, thereby improving the binding affinity and pharmacokinetic profiles of new therapeutic agents. Beyond pharmaceuticals, it finds application in the development of advanced polymers and specialty materials where thermal stability and chemical resistance are paramount. The high purity level ensures minimal side reactions, leading to improved yields in multi-step synthesis routes and reducing waste generation.
Quality Assurance and Safety Handling
Our facility adheres to strict Good Manufacturing Practices to ensure product integrity and traceability. Each shipment is accompanied by a comprehensive Certificate of Analysis verifying identity and purity levels. Regarding safety, isocyanates are reactive compounds that require careful handling and specific storage conditions. We recommend storing this product in a cool, ventilated place away from moisture and incompatible materials such as strong oxidizers or amines. Proper personal protective equipment should be worn during handling to prevent inhalation or skin contact. Our packaging options include 200 kg drums, with custom packaging available upon request to suit specific logistical needs and regulatory requirements.
Global Supply and Technical Support
As a global manufacturer, we are committed to providing reliable supply chains for our international clientele in the chemical sector. We understand the importance of timely delivery in research and production schedules. Our technical team is available to provide synthesis route guidance and support regarding the integration of this intermediate into your specific manufacturing process. For inquiries regarding bulk pricing, sample requests, or custom synthesis capabilities, please contact our sales department. We strive to be your trusted partner in sourcing high-performance chemical building blocks for innovative projects.
