4-(Trifluoromethoxy)phenylacetonitrile
- CAS No.49561-96-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade 4-(Trifluoromethoxy)phenylacetonitrile (CAS 49561-96-8) designed for advanced organic synthesis. High purity ≥98.0% ensures reliable reaction outcomes for pharmaceutical and agrochemical manufacturing.
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Product Overview
4-(Trifluoromethoxy)phenylacetonitrile is a highly specialized fluorinated organic intermediate characterized by the presence of a trifluoromethoxy group attached to the phenyl ring. This unique structural feature imparts significant metabolic stability and enhanced lipophilicity to downstream molecules, making it an invaluable building block in modern medicinal chemistry and agrochemical development. Our facility produces this compound under strict quality control standards to ensure consistency across batches, supporting both research-scale experiments and large-scale industrial production needs.
The introduction of the trifluoromethoxy moiety is a strategic move in drug design, often used to modulate the electronic properties and binding affinity of active pharmaceutical ingredients. As a trusted global manufacturer, we provide this key intermediate with comprehensive technical support to assist chemists in optimizing their synthetic routes.
Technical Specifications
We adhere to rigorous analytical protocols to guarantee the quality of every shipment. The following table outlines the key physical and chemical properties of our standard grade product.
| Parameter | Specification |
|---|---|
| CAS Number | 49561-96-8 |
| Molecular Formula | C9H6F3NO |
| Molecular Weight | 201.145 g/mol |
| Appearance | White to yellow solid or Colorless to yellow liquid |
| Assay (Purity) | ≥98.0% |
| Melting Point | 30-33 °C |
| Boiling Point | 224.6±35.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Refractive Index | 1.461 |
| Flash Point | 89.6±25.9 °C |
Industrial Applications
This fluorinated nitrile serves as a critical precursor in the synthesis of complex organic molecules. Its primary applications include:
- Pharmaceutical Intermediates: Used in the development of novel therapeutics where metabolic stability is crucial.
- Agrochemical Synthesis: Employed in the creation of advanced pesticides and herbicides with improved environmental profiles.
- Material Science: Utilized in the production of specialized polymers and liquid crystals.
- Research and Development: Essential for academic and industrial labs focusing on fluorine chemistry.
Quality Assurance and Logistics
Quality is the cornerstone of our manufacturing process. Each batch of 4-(Trifluoromethoxy)phenylacetonitrile undergoes thorough testing using HPLC and NMR spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every order to ensure full transparency and compliance with your internal quality standards.
We offer flexible packaging options, typically supplying in 25 kg drums, but can accommodate custom requirements based on project volume. Proper storage in a cool, ventilated area is recommended to maintain product integrity. Our logistics network ensures timely global delivery, minimizing supply chain disruptions for our partners.
