Intermediates

4'-(Trifluoromethyl)acetophenone

  • CAS No.709-63-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4'-(Trifluoromethyl)acetophenone (CAS 709-63-7) designed for pharmaceutical synthesis and organic research. Reliable supply with comprehensive COA.

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Product Technical Details

Product Overview

4'-(Trifluoromethyl)acetophenone is a specialized fluorinated organic compound widely recognized for its utility in modern medicinal chemistry and advanced organic synthesis. As a key building block, this intermediate features a trifluoromethyl group attached to the phenyl ring, which significantly enhances the metabolic stability and lipophilicity of downstream pharmaceutical candidates. Our manufacturing process ensures consistent quality, making it an ideal choice for research institutions and pharmaceutical companies developing novel therapeutic agents.

We understand the critical nature of supply chain reliability in the chemical industry. Therefore, we maintain robust production capabilities to meet global demand for high-performance fluorinated intermediates. This product serves as a foundational material for constructing complex molecular architectures required in drug discovery programs.

Chemical Properties and Specifications

The chemical integrity of 4'-(Trifluoromethyl)acetophenone is maintained through rigorous quality control protocols. Each batch undergoes comprehensive testing to verify physical constants and purity levels. The presence of the trifluoromethyl moiety imparts unique electronic properties that are essential for specific catalytic reactions and coupling processes. Below are the standard technical specifications for our commercial grade material.

ParameterSpecification
CAS Number709-63-7
Molecular FormulaC9H7F3O
Molecular Weight188.15 g/mol
AppearanceWhite solid
Purity≥98.0%
Melting Point30-33 °C
Boiling Point79-80 °C at 8 mm Hg
Density0.92 g/cm3
Refractive Index1.4604

Industrial Applications

This fluorinated acetophenone derivative is primarily utilized in the synthesis of sophisticated pharmaceutical intermediates. It plays a vital role in the development of P2Y1 antagonists, which are investigated for antithrombotic applications. Furthermore, it serves as a precursor in the creation of agents targeting myeloid cell leukemia pathways. The versatility of this compound allows chemists to introduce trifluoromethyl groups efficiently, a common strategy to improve drug bioavailability and binding affinity.

Beyond pharmaceuticals, this compound is valuable in agrochemical research and material science where fluorinated aromatics are required. Our team supports customers with technical data to facilitate smooth integration into their respective synthesis routes. We emphasize responsible use and compliance with all local regulations regarding chemical handling and distribution.

Quality Assurance and Packaging

Quality is the cornerstone of our operation. Every drum of 4'-(Trifluoromethyl)acetophenone is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. We employ stable packaging solutions to prevent degradation during transit. Standard packing includes 25kg drums, though we accommodate custom requirements based on project scale. Storage recommendations include keeping containers closed at room temperature under normal handling conditions to maintain stability.

As a global manufacturer, we offer competitive bulk pricing and reliable logistics support. Our commitment to excellence ensures that researchers receive materials that meet the highest standards of purity and consistency. Contact our sales team for detailed quotations and safety data sheets.