4-(Trifluoromethyl)Benzoic Acid
- CAS No.455-24-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-(Trifluoromethyl)Benzoic Acid (CAS 455-24-3) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical manufacturing.
Request Bulk PricingProduct Technical Details
Product Overview
4-(Trifluoromethyl)Benzoic Acid is a critical fluorinated building block extensively utilized in modern organic synthesis and medicinal chemistry. As a key intermediate, this compound features a robust trifluoromethyl group attached to the para position of the benzoic acid structure, imparting unique electronic and lipophilic properties essential for drug design. Our manufacturing process ensures exceptional consistency, making it an ideal choice for researchers and industrial producers aiming to develop high-performance pharmaceutical agents, agrochemicals, and functional materials.
The introduction of the trifluoromethyl moiety often enhances metabolic stability and bioavailability in final drug products. Consequently, demand for high-quality 4-(Trifluoromethyl)Benzoic Acid has surged within the global chemical market. We specialize in producing this compound under stringent quality management systems, guaranteeing that every batch meets or exceeds international standards for purity and physical characteristics.
Key Specifications
Quality assurance is paramount in our production facility. Each lot undergoes rigorous analytical testing using advanced chromatography and spectroscopy methods to verify identity and purity. The following table outlines the standard technical specifications for our commercial grade material:
| Parameter | Value |
|---|---|
| Chemical Name | 4-(Trifluoromethyl)Benzoic Acid |
| CAS Number | 455-24-3 |
| Molecular Formula | C8H5F3O2 |
| Molecular Weight | 190.12 g/mol |
| Appearance | White to off-white powder |
| Assay (Purity) | ≥99.0% |
| Moisture Content | ≤0.2% |
| Melting Point | 219-220°C |
| Density | 1.403 g/cm3 |
Industrial Applications
This fluorinated intermediate serves as a versatile precursor in various synthetic pathways. In the pharmaceutical sector, it is frequently employed in the synthesis of kinase inhibitors, anti-inflammatory agents, and central nervous system therapeutics. The electron-withdrawing nature of the trifluoromethyl group facilitates specific coupling reactions, allowing chemists to construct complex molecular architectures with high precision.
Beyond healthcare, 4-(Trifluoromethyl)Benzoic Acid finds applications in agrochemical development, where it contributes to the efficacy of herbicides and pesticides. Additionally, it is used in the production of liquid crystals and polymeric materials where thermal stability and chemical resistance are required. Our team provides comprehensive technical support to help clients optimize their synthesis routes and integrate this material seamlessly into their manufacturing processes.
Storage and Handling
To maintain optimal quality, 4-(Trifluoromethyl)Benzoic Acid should be stored in a cool, ventilated area away from direct sunlight and moisture. The standard packaging consists of 25 kg drums, though we offer custom packaging solutions to accommodate specific logistical requirements. Proper handling procedures include using personal protective equipment such as gloves and safety goggles. We provide full documentation, including Certificates of Analysis (COA) and Safety Data Sheets (SDS), with every shipment to ensure compliance with global safety regulations.
