4-Trifluoromethylbenzoyl Chloride
- CAS No.329-15-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 4-Trifluoromethylbenzoyl Chloride (CAS 329-15-7) is a premium fluorinated intermediate designed for pharmaceutical synthesis and organic research applications.
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Product Overview
4-Trifluoromethylbenzoyl Chloride is a highly valued fluorinated chemical intermediate widely utilized in modern organic synthesis and medicinal chemistry. As a key building block, this compound features a trifluoromethyl group attached to the benzoyl chloride structure, enhancing its reactivity and lipophilicity for various downstream transformations. Our facility produces this material under strict quality control standards to ensure consistency for research and industrial scale applications.
The introduction of fluorine atoms into organic molecules often significantly improves metabolic stability and bioavailability. Consequently, this reagent serves as a critical precursor in the development of advanced pharmaceutical compounds. We supply this product with high purity specifications to support efficient synthesis routes without requiring extensive purification steps.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Trifluoromethylbenzoyl Chloride |
| CAS Number | 329-15-7 |
| Molecular Formula | C8H4ClF3O |
| Molecular Weight | 208.57 g/mol |
| Purity | ≥98.0% |
| Appearance | Colorless or yellow liquid |
| Density | 1.404 g/cm3 |
| Boiling Point | 188-190 °C |
| Melting Point | -3 °C |
Industrial Applications
This fluorinated acyl chloride is primarily employed in the synthesis of complex pharmaceutical intermediates. It acts as an essential reagent for introducing the 4-trifluoromethylphenyl moiety into target molecules. Common uses include the preparation of bioactive compounds for cardiovascular research and oncology studies. The high reactivity of the acid chloride group allows for efficient amide and ester formation under controlled conditions.
Researchers utilize this building block for developing novel therapeutic agents where fluorine substitution is required to modulate pharmacokinetic properties. It is suitable for multi-step synthesis processes in both laboratory and pilot plant settings. Our team supports clients with technical data to ensure safe and effective integration into their specific manufacturing processes.
Quality And Safety
We adhere to rigorous quality assurance protocols. Each batch is accompanied by a Certificate of Analysis (COA) verifying purity and physical constants. Safety is paramount when handling acyl chlorides due to their corrosive nature and moisture sensitivity. Proper personal protective equipment including gloves and eye protection must be worn during handling.
- Strict moisture control during storage and usage
- Compatible with standard organic synthesis protocols
- Batch traceability for quality compliance
- Global shipping capabilities with proper hazard classification
Storage And Packaging
To maintain stability, 4-Trifluoromethylbenzoyl Chloride should be stored in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and bases. Containers must remain tightly closed when not in use to prevent hydrolysis from atmospheric moisture. We offer flexible packaging options including fluorinated HDPE bottles in various sizes ranging from grams to kilograms to meet diverse research and production needs.
