Intermediates

4-Trifluoromethylbenzyl Chloride

  • CAS No.939-99-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Trifluoromethylbenzyl chloride (CAS 939-99-1), a key fluorinated intermediate for agrochemical synthesis.

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Product Technical Details

Product Overview

4-Trifluoromethylbenzyl chloride is a high-value fluorinated aromatic building block widely employed in the synthesis of advanced agrochemical intermediates. With a molecular formula of C8H6ClF3 and a molecular weight of 194.58 g/mol, this compound features a reactive benzylic chloride group adjacent to a strongly electron-withdrawing trifluoromethyl moiety, making it highly suitable for nucleophilic substitution reactions in fine chemical manufacturing.

Specifications

Molecular FormulaC8H6ClF3
Molecular Weight194.58 g/mol
Density1.315 g/cm³
Melting Point19°C
Boiling Point68°C
Flash Point165°F (74°C)
Refractive Index1.464
AppearanceColourless to light yellow liquid
Purity (GC)≥99.0%

Industrial Applications

This compound serves primarily as a critical synthetic intermediate in the production of rodenticides such as Flocoumafen, leveraging its fluorinated aromatic scaffold to enhance bioactivity and environmental stability. Its robust reactivity profile enables efficient derivatization in multi-step organic syntheses, particularly in the development of complex pharmaceutical APIs and advanced crop protection agents.

  • Ideal for nucleophilic displacement and cross-coupling reactions
  • Enables introduction of the 4-(trifluoromethyl)benzyl pharmacophore
  • Compatible with standard industrial-scale handling protocols

Handling and Storage

Store in a cool, dry, and well-ventilated area away from heat, sparks, and incompatible materials such as strong bases or oxidizing agents. Supplied in 200 kg drums with custom packaging available upon request. Safety data sheets and certificates of analysis (COA) are provided with every batch to ensure traceability and compliance with international quality standards.