Intermediates

4-(Trifluoromethylthio)aniline

  • CAS No.372-16-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-(Trifluoromethylthio)aniline (CAS 372-16-7) designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

4-(Trifluoromethylthio)aniline is a specialized fluorinated organic compound that serves as a critical building block in modern chemical synthesis. Characterized by the presence of a trifluoromethylthio group attached to the para position of the aniline ring, this molecule offers unique electronic and steric properties that are highly valued in the development of advanced pharmaceuticals and agrochemicals. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for research and industrial scale applications.

The incorporation of the SCF3 moiety significantly enhances the lipophilicity and metabolic stability of downstream products. This makes 4-(Trifluoromethylthio)aniline a preferred precursor for medicinal chemists aiming to optimize the pharmacokinetic profiles of new drug candidates. As a trusted global manufacturer, we adhere to strict quality control standards to deliver materials that meet the rigorous demands of the life sciences industry.

Technical Specifications

Our production facility utilizes advanced distillation and purification techniques to achieve superior assay levels. The physical properties of this compound facilitate easy handling and integration into various synthetic routes. Below are the key technical parameters verified through our internal quality assurance protocols.

PropertySpecification
CAS Number372-16-7
Molecular FormulaC7H6F3NS
Molecular Weight193.189
AppearanceLight yellow liquid
Assay≥98.0%
Density1.4±0.1 g/cm3
Boiling Point183.0±40.0 °C at 760 mmHg
Flash Point64.5±27.3 °C
Refractive Index1.532

Industrial Applications

This fluorinated aniline derivative is primarily utilized as an intermediate in the synthesis of complex organic molecules. Its applications span across multiple sectors including pharmaceutical development, where it contributes to the creation of novel therapeutic agents. Additionally, it finds use in the agrochemical industry for the production of high-performance crop protection chemicals. The stability of the trifluoromethylthio group allows for diverse chemical transformations, enabling chemists to construct intricate molecular architectures with precision.

Researchers value this compound for its reliability in cross-coupling reactions and nucleophilic substitutions. Whether used in small-scale laboratory experiments or large-scale manufacturing processes, 4-(Trifluoromethylthio)aniline provides a robust foundation for innovation. Our team provides comprehensive technical support to assist clients in integrating this material into their specific synthesis routes effectively.

Quality Assurance and Safety

We understand that consistency is paramount in chemical manufacturing. Every batch of 4-(Trifluoromethylthio)aniline undergoes rigorous testing using state-of-the-art analytical instrumentation such as HPLC and GC-MS. A Certificate of Analysis (COA) is provided with every shipment to verify compliance with specified purity levels. Our commitment to quality ensures that customers receive materials that perform predictably in their applications.

Safety is a core component of our operational framework. This product should be stored in a cool, ventilated place away from incompatible substances. Proper personal protective equipment (PPE) is recommended during handling to ensure workplace safety. We offer flexible packaging options, including 200 kg drums, to accommodate various logistical requirements while maintaining product integrity during transit. Partner with us for reliable supply chains and premium chemical solutions.