Intermediates

4H-3,1-Benzoxazine-2,4(1H)-dione

  • CAS No.118-48-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride) for agrochemical synthesis. Reliable supply with ≥99.0% assay and global shipping options.

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Product Technical Details

Product Overview

4H-3,1-Benzoxazine-2,4(1H)-dione, commonly known in the industry as Isatoic Anhydride, is a vital heterocyclic organic compound utilized extensively in fine chemical synthesis. With the CAS registry number 118-48-9, this substance serves as a foundational building block for various agrochemical and pharmaceutical applications. Our manufacturing process ensures exceptional stability and reactivity, making it an ideal candidate for complex organic transformations. The compound features a fused benzene and oxazine ring structure, which provides unique chemical properties suitable for nucleophilic substitution reactions.

We specialize in producing this intermediate with stringent quality controls to meet international standards. The material is characterized by its high thermal stability and specific solubility profiles, which facilitate efficient downstream processing. As a leading global manufacturer, we understand the critical nature of supply chain consistency for production facilities relying on this key intermediate for herbicide synthesis.

Technical Specifications

ParameterSpecification
CAS Number118-48-9
Molecular FormulaC8H5NO3
Molecular Weight163.13 g/mol
AppearanceWhite or light yellow crystal
Assay (Purity)≥99.0%
Melting Point233 °C (dec.)
Loss on Drying≤0.5%
Total Ash≤0.5%
Density1.4±0.1 g/cm3

Industrial Applications

The primary application of 4H-3,1-Benzoxazine-2,4(1H)-dione lies in the agrochemical sector, specifically as a crucial intermediate in the synthesis of Bentazone (CAS 25057-89-0), a widely used herbicide. The high purity levels we maintain ensure minimal byproduct formation during the synthesis route, optimizing yield and reducing waste disposal costs for our clients. Beyond herbicide production, this compound exhibits versatility in organic synthesis, serving as a precursor for various quinazoline derivatives and other heterocyclic structures.

Our technical team supports customers with detailed manufacturing process insights, ensuring seamless integration into existing production lines. The compound's reactivity profile allows for efficient acylation and condensation reactions, making it a preferred choice for R&D departments focusing on new agrochemical formulations. We provide comprehensive documentation to support regulatory compliance in multiple jurisdictions.

Quality Assurance and Storage

Quality is paramount in our production facility. Each batch of 4H-3,1-Benzoxazine-2,4(1H)-dione undergoes rigorous testing using advanced analytical methods such as HPLC and GC-MS to verify purity and identity. We provide a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. Our packaging is designed to maintain product integrity during transit, typically supplied in 25kg drums, though custom packaging solutions are available upon request.

Proper storage is essential to maintain the chemical stability of this anhydride. We recommend storing the product in a cool, dry, and well-ventilated area. Containers must be kept tightly closed to prevent moisture absorption, as the compound may decompose upon exposure to water. Adhering to these storage guidelines ensures the material retains its specified assay and physical properties throughout its shelf life. Contact our sales team for bulk pricing and availability.