Intermediates

5-(2-Chloroethyl)-2,3-Dihydro-1-Benzofuran

  • CAS No.943034-50-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate essential for Darifenacin synthesis. Available in bulk with strict quality control and comprehensive documentation.

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Product Technical Details

Product Overview

5-(2-Chloroethyl)-2,3-Dihydro-1-Benzofuran is a specialized organic compound designed for use in advanced pharmaceutical synthesis. This benzofuran derivative serves as a critical building block in the production of active pharmaceutical ingredients, specifically functioning as a key intermediate in the manufacturing pathway of Darifenacin. Our facility ensures that every batch meets rigorous chemical standards, providing reliability for downstream drug production.

The molecular structure features a chloroethyl side chain attached to the dihydrobenzofuran core, enabling specific nucleophilic substitution reactions required in multi-step API synthesis. We prioritize consistency and purity to support efficient manufacturing processes for our global partners.

Technical Specifications

ParameterValue
CAS Number943034-50-2
Molecular FormulaC10H11ClO
Molecular Weight182.647 g/mol
AppearanceWhite crystalline powder
Assay (HPLC)≥98.0%
Moisture Content≤1.0%
Boiling Point284.4±9.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point128.4±12.8 °C

Industrial Applications

This compound is primarily utilized as a precursor in the synthesis of Darifenacin and Darifenacin hydrobromide, which are therapeutic agents used in urology. The high purity level of our intermediate ensures minimal impurity carryover into the final API, facilitating smoother regulatory approval processes and consistent drug performance.

Chemical manufacturers and pharmaceutical companies rely on this material for its reactivity and stability under standard processing conditions. It is suitable for large-scale production environments where batch-to-batch consistency is paramount.

Quality Assurance And Storage

  • Produced under strict quality management systems with full traceability.
  • Certificate of Analysis (COA) provided with every shipment.
  • Packaged in 25 kg drums or customized according to client requirements.
  • Storage recommended in a cool, ventilated area away from direct sunlight and moisture.
  • Global shipping capabilities with secure handling protocols.

We are committed to supplying high-quality chemical intermediates that meet international standards. Our technical team is available to support your synthesis route optimization and provide detailed specifications upon request.