Intermediates

5-Amino-2,3-dihydrobenzofuran

  • CAS No.42933-43-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Amino-2,3-dihydrobenzofuran (CAS 42933-43-7) designed for pharmaceutical intermediate synthesis. Available in bulk quantities with certified quality assurance.

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Product Technical Details

Product Overview

5-Amino-2,3-dihydrobenzofuran is a specialized organic compound that serves as a critical building block in the realm of medicinal chemistry and pharmaceutical development. Characterized by its fused bicyclic structure containing both benzene and furan rings with an amino substitution, this molecule offers unique reactivity profiles essential for complex synthetic pathways. Our facility produces this intermediate under strict quality control standards to ensure consistency and reliability for downstream applications.

As a key precursor, this chemical enables the construction of diverse pharmacophores found in modern therapeutic agents. The presence of the amino group facilitates various derivatization reactions, including acylation, alkylation, and heterocycle formation, making it a versatile tool for research and industrial synthesis teams aiming to develop novel drug candidates.

Technical Specifications

ParameterValue
CAS Number42933-43-7
Molecular FormulaC8H9NO
Molecular Weight135.163 g/mol
AppearanceYellow to dark brown powder
Assay (Purity)≥98.0%
Density1.2±0.1 g/cm3
Boiling Point289.4±29.0 °C at 760 mmHg
Flash Point151.5±17.5 °C

Industrial Applications

This compound is predominantly utilized as a pharmaceutical intermediate in the synthesis of advanced organic molecules. Its structural framework is particularly valuable in the design of compounds targeting neurological and cardiovascular pathways. Researchers leverage the dihydrobenzofuran scaffold to enhance metabolic stability and bioavailability in lead optimization phases.

Beyond pharmaceuticals, this intermediate supports the development of agrochemicals and fine chemicals where specific aromatic amine functionalities are required. The high purity grade ensures minimal impurity carryover into final products, reducing purification burdens and improving overall process efficiency for manufacturing partners.

Quality Assurance and Storage

We adhere to rigorous manufacturing processes to maintain industrial purity levels. Each batch undergoes comprehensive analytical testing, including HPLC and NMR spectroscopy, to verify identity and potency. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specified parameters.

For optimal stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper sealing is recommended to prevent oxidation or degradation over time. We offer flexible packaging options, including 25 kg drums, and can accommodate custom requirements to suit specific logistical needs for global distribution.