Intermediates

5-Amino-2,4-dichloroanisole

  • CAS No.98446-49-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Amino-2,4-dichloroanisole (CAS 98446-49-2) designed for pharmaceutical synthesis. Reliable supply for Bosutinib production with strict quality control.

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Product Technical Details

Product Overview

5-Amino-2,4-dichloroanisole is a highly specialized aromatic amine derivative that serves as a critical building block in modern pharmaceutical synthesis and organic chemistry. Recognized globally by its CAS registry number 98446-49-2, this compound is engineered to meet the rigorous demands of medicinal chemistry laboratories and large-scale production facilities alike. Our advanced manufacturing process ensures consistent molecular integrity, making it an ideal candidate for complex organic transformations requiring high precision. The substance typically presents as a pale yellow solid, indicating high stability under standard storage conditions when handled correctly. We prioritize purity levels that exceed general industry standards to facilitate downstream reactions with minimal impurity profiles, ensuring smoother synthesis pathways for our clients.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates used in drug development. Each batch undergoes comprehensive analytical testing using gas chromatography and other advanced methodologies to verify composition. The following table outlines the key physical and chemical parameters that define our premium grade material. These specifications are verified against international pharmacopoeia standards where applicable to ensure compatibility with global regulatory requirements.

ParameterSpecification
CAS Number98446-49-2
Molecular FormulaC7H7Cl2NO
Molecular Weight192.04 g/mol
Purity (GC)≥98.0%
AppearancePale yellow solid
Melting Point51°C
Boiling Point290.1°C
Density1.375 g/cm3
Flash Point129.3°C

Industrial Applications

The primary application of 5-Amino-2,4-dichloroanisole lies in the synthesis of advanced kinase inhibitors, most notably as a key intermediate in the production of Bosutinib. This pharmaceutical agent is crucial for treating specific types of leukemia, highlighting the absolute importance of supply chain reliability and material consistency. Beyond this specific pathway, the compound serves as a versatile nucleophile in various substitution reactions within organic chemistry. Chemists utilize its specific reactivity profile to construct complex heterocyclic systems essential for new drug discovery. Our material supports both research and development phases as well as commercial manufacturing scales without compromise. We understand the critical nature of timeline adherence in drug development pipelines and strive to support our partners accordingly.

Quality Assurance and Safety

Our facility operates under strict quality management systems to ensure every drum meets the declared specifications upon arrival. We provide a Certificate of Analysis (COA) with every shipment, detailing batch-specific test results for full transparency. Safety is equally prioritized in our operations; this material is classified under UN1993 with a hazard class of 3, requiring careful handling. Proper handling procedures must be followed to ensure workplace safety and environmental compliance. We recommend storage in a cool, ventilated area away from incompatible substances to maintain stability. Our packaging options include standard 25 kg drums, with customization available to suit specific logistical requirements. We are committed to delivering not just chemicals, but peace of mind through compliance and consistency.

Global Supply Capabilities

As a global manufacturer, we maintain robust inventory levels to prevent production delays for our valued partners. Our logistics network ensures timely delivery to major pharmaceutical hubs worldwide, regardless of location. We offer competitive bulk pricing structures for long-term contracts to support cost-effective manufacturing. Our technical support team is available to assist with synthesis route optimization and regulatory documentation needs. Choose us for a partnership built on transparency, quality, and scientific excellence. Contact our sales department today to request a quote or sample for your evaluation and begin your project with confidence.