5-Amino-2-chlorobenzotrifluoride
- CAS No.320-51-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used in Sorafenib synthesis. Available in bulk with full documentation.
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Product Overview
5-Amino-2-chlorobenzotrifluoride is a specialized organic compound serving as a vital building block in the pharmaceutical industry. This aromatic amine derivative is characterized by its unique chemical structure, incorporating both chloro and trifluoromethyl substituents on the benzene ring. Our facility produces this material under strict quality control protocols to ensure consistency for downstream synthesis operations. It is primarily recognized for its role in the manufacturing of advanced kinase inhibitors.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 5-Amino-2-chlorobenzotrifluoride |
| CAS Number | 320-51-4 |
| Molecular Formula | C7H5ClF3N |
| Molecular Weight | 195.57 g/mol |
| Purity (GC) | ≥98.0% |
| Melting Point | 35-37°C |
| Boiling Point | 85°C |
| Density | 1.425 g/cm³ |
| Refractive Index | 1.515 |
Industrial Applications
This compound is extensively utilized as a key intermediate in the synthesis of Sorafenib, a multi-kinase inhibitor used in oncology treatments. The presence of the trifluoromethyl group enhances the metabolic stability and lipophilicity of the final drug molecule. Beyond oncology, this chemical serves as a versatile precursor for various agrochemical and fine chemical applications requiring halogenated aromatic amines. Our clients leverage this material for custom synthesis projects demanding high regioselectivity.
- Primary intermediate for Sorafenib production
- Precursor for kinase inhibitor development
- Building block for fluorinated pharmaceuticals
- Used in agrochemical research and development
Quality Assurance and Safety
We maintain a robust quality management system to guarantee product integrity. Each batch undergoes rigorous testing via gas chromatography to confirm purity levels exceeding 98 percent. Safety data indicates this substance falls under UN2811 with a hazard class of 6.1, requiring careful handling during transport and storage. Our technical team provides comprehensive Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS) with every shipment to ensure regulatory compliance.
Packaging and Logistics
Standard packaging consists of 25 kg drums lined with protective materials to prevent moisture absorption and contamination. We offer flexible packaging solutions tailored to specific customer requirements, including bulk containers for large-scale manufacturing. Storage recommendations include keeping the product in a cool, ventilated area away from direct sunlight and oxidizing agents. Our global logistics network ensures timely delivery while adhering to all international hazardous material shipping regulations.
