Intermediates

5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine

  • CAS No.380380-64-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity pharmaceutical intermediate used in the synthesis of Tedizolid. Available in bulk quantities with comprehensive quality documentation.

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Product Technical Details

Product Overview

5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine is a specialized organic compound designed for advanced pharmaceutical synthesis. This heterocyclic building block features a pyridine core substituted with a bromine atom and a methylated tetrazole ring, providing unique reactivity profiles essential for constructing complex antibiotic structures. As a critical intermediate in the production of Tedizolid, this compound meets stringent quality standards required for modern drug development.

Our manufacturing facility employs state-of-the-art synthesis techniques to ensure consistent batch-to-batch reliability. The compound is characterized by high chemical stability and optimal solubility properties, making it an ideal candidate for multi-step organic synthesis pathways. We prioritize purity and safety throughout the production lifecycle, adhering to international chemical management protocols.

Technical Specifications

Quality control is paramount in pharmaceutical intermediate supply. Each batch undergoes rigorous analytical testing using HPLC, NMR, and mass spectrometry to verify structural integrity and purity levels. The following table outlines the key physical and chemical parameters guaranteed for this product:

ParameterSpecification
CAS Number380380-64-3
Molecular FormulaC7H6BrN5
Molecular Weight240.060 g/mol
AppearanceWhite powder
Assay≥98.0%
Total Impurity≤2.0%
Moisture Content≤1.0%
Density1.9±0.1 g/cm3
Boiling Point375.2±52.0 °C at 760 mmHg
Flash Point180.7±30.7 °C

Industrial Applications

This compound serves primarily as a key precursor in the synthesis of oxazolidinone antibiotics, specifically Tedizolid. The bromine substituent allows for versatile cross-coupling reactions, while the tetrazole moiety contributes to the biological activity profile of the final active pharmaceutical ingredient. Researchers and process chemists utilize this intermediate to optimize reaction yields and minimize downstream purification challenges.

Beyond antibiotic synthesis, this chemical finds utility in medicinal chemistry research focused on nitrogen-containing heterocycles. Its structural features enable the exploration of structure-activity relationships in novel therapeutic candidates. We support R&D teams with flexible packaging options and timely delivery to accelerate project timelines.

Quality Assurance and Storage

We maintain a robust quality management system to ensure product integrity from synthesis to shipment. A Certificate of Analysis (COA) is provided with every order, detailing test results against specified parameters. Our packaging solutions include 25 kg drums, with custom configurations available upon request to suit specific logistical requirements.

For optimal stability, store this material in a cool, ventilated area away from direct sunlight and moisture. Proper handling procedures should be followed in accordance with safety data sheets. Our global distribution network ensures reliable supply chains for manufacturers and research institutions worldwide, supporting continuous production schedules and innovation pipelines.