5-Bromo-2,3-difluorophenol
- CAS No.186590-26-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Bromo-2,3-difluorophenol designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical intermediates.
Request Bulk PricingProduct Technical Details
Product Overview
5-Bromo-2,3-difluorophenol represents a critical fluorinated aromatic intermediate utilized extensively in modern organic synthesis and chemical manufacturing. As a specialized building block, this compound offers unique reactivity profiles due to the strategic presence of both bromine and fluorine substituents on the phenolic ring structure. Our advanced manufacturing process ensures exceptional chemical purity, making it an ideal candidate for complex multi-step synthesis routes required in the pharmaceutical and agrochemical sectors.
The specific positioning of halogen atoms allows for versatile coupling reactions, including Suzuki-Miyaura cross-couplings and nucleophilic aromatic substitutions. This chemical versatility makes the compound a preferred choice for research and development teams aiming to introduce specific functional groups into larger molecular architectures. We prioritize batch-to-batch consistency and reliability, ensuring that every shipment meets the rigorous demands of industrial-scale production.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 186590-26-1 |
| Molecular Formula | C6H3BrF2O |
| Molecular Weight | 208.988 g/mol |
| Appearance | Off-White to light pink solid |
| Assay | ≥98.0% |
| Melting Point | 223 °C (dec.) |
| Boiling Point | 212.2±35.0 °C at 760 mmHg |
| Density | 1.9±0.1 g/cm3 |
| Flash Point | 82.1±25.9 °C |
| Refractive Index | 1.550 |
Industrial Applications
Primarily designated as a key intermediate for organic synthesis, this fluorinated phenol derivative serves as a foundational component in the creation of advanced materials and active pharmaceutical ingredients. The high electronegativity of the fluorine atoms enhances metabolic stability in potential drug candidates, while the bromine handle facilitates further functionalization through palladium-catalyzed reactions. Industries relying on precise chemical architectures benefit significantly from the stability and reactivity balance offered by this substance.
Common use cases include the development of novel therapeutic agents, crop protection chemicals, and specialized polymers requiring fluorinated motifs. Our supply chain is optimized to support both pilot-scale research and large-scale industrial production requirements. Clients receive comprehensive technical documentation to ensure seamless integration into their existing manufacturing processes without disruption.
Quality Assurance and Handling
Quality control is paramount in our production facility. Each batch undergoes rigorous testing using advanced analytical techniques such as High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) to verify identity and purity levels. A Certificate of Analysis (COA) is provided with every shipment, guaranteeing compliance with specified international standards. We adhere to strict safety protocols during packaging and transportation to maintain product integrity throughout the logistics chain.
- Packaged in 25 kg drums for optimal physical protection.
- Custom packaging solutions available upon specific customer request.
- Stored in a cool, ventilated environment away from moisture and heat.
- Shelf life maintained under recommended storage conditions for extended periods.
For detailed safety data sheets or specific technical inquiries regarding synthesis pathways, our support team is available to assist global partners promptly. We are committed to delivering high-performance chemical solutions that drive innovation and efficiency in your projects.
