Intermediates

5-Bromo-2-chloro-3-fluoropyridine

  • CAS No.831203-13-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Bromo-2-chloro-3-fluoropyridine designed for advanced organic synthesis. Reliable supply with comprehensive COA and global shipping options.

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Product Technical Details

Product Overview

5-Bromo-2-chloro-3-fluoropyridine is a highly specialized heterocyclic compound serving as a critical building block in modern organic synthesis. This halogenated pyridine derivative features a unique substitution pattern that enables versatile chemical transformations, making it indispensable for pharmaceutical research and agrochemical development. Our manufacturing process ensures exceptional batch-to-batch consistency and high purity levels suitable for demanding synthetic routes.

As a key intermediate, this compound facilitates cross-coupling reactions and nucleophilic substitutions due to the reactive halogen positions on the pyridine ring. The presence of bromine, chlorine, and fluorine atoms allows chemists to selectively functionalize the molecule, enabling the construction of complex molecular architectures required in medicinal chemistry and material science applications.

Technical Specifications

ParameterValue
CAS Number831203-13-5
Molecular FormulaC5H2BrClFN
Molecular Weight210.432 g/mol
AppearanceWhite to off-white crystalline powder
Assay>=98.0%
Density1.8 +/- 0.1 g/cm3
Boiling Point195.3 +/- 35.0 degrees C at 760 mmHg
Flash Point71.9 +/- 25.9 degrees C

Industrial Applications

This fluorinated pyridine intermediate is extensively utilized in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. Its structural properties make it an ideal candidate for developing kinase inhibitors, receptor modulators, and other therapeutic agents. Additionally, it finds application in the production of advanced agrochemicals where specific halogen placement enhances biological activity and environmental stability.

  • Pharmaceutical intermediate for drug discovery programs
  • Building block for heterocyclic compound synthesis
  • Reagent for cross-coupling reactions such as Suzuki or Buchwald
  • Component in agrochemical formulation development
  • Material science research for organic electronics

Quality Assurance and Packaging

We adhere to strict quality control protocols to ensure every shipment meets international standards. Each batch undergoes rigorous testing using HPLC and NMR spectroscopy to verify identity and purity. A comprehensive Certificate of Analysis (COA) is provided with every order to support regulatory compliance and quality documentation.

Standard packaging consists of 25 kg drums, ensuring safe transport and storage. Custom packaging solutions are available upon request to meet specific logistical requirements. Our global supply chain network guarantees timely delivery to laboratories and manufacturing facilities worldwide.

Storage and Handling

To maintain optimal stability, 5-Bromo-2-chloro-3-fluoropyridine should be stored in a cool, well-ventilated area away from direct sunlight and moisture. Containers must be kept tightly closed when not in use. Standard laboratory safety precautions apply, including the use of appropriate personal protective equipment during handling. Please refer to the Safety Data Sheet (SDS) for detailed hazard information and emergency procedures.