Intermediates

5-Bromo-2-chloroanisole

  • CAS No.16817-43-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 5-Bromo-2-chloroanisole (CAS 16817-43-9) designed for complex organic synthesis workflows. Available in bulk with strict quality control.

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Product Technical Details

Product Overview

5-Bromo-2-chloroanisole is a highly specialized halogenated aromatic compound that serves as a critical building block in modern organic chemistry. Designed for rigorous industrial applications, this substance features a unique substitution pattern on the benzene ring, making it an invaluable precursor for the development of advanced pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures exceptional consistency, providing researchers and production facilities with a reliable source of high-purity material.

As a key intermediate, this compound facilitates various coupling reactions and nucleophilic substitutions. Its structural stability and reactivity profile allow chemists to construct complex molecular architectures efficiently. We prioritize quality assurance at every stage of production, from raw material sourcing to final packaging, ensuring that every batch meets stringent international standards for chemical purity and safety.

Key Specifications

To support precise laboratory work and large-scale production needs, we maintain tight control over physical and chemical parameters. The following table outlines the standard specifications for our commercial grade material.

Parameter Specification
Chemical Name 5-Bromo-2-chloroanisole
CAS Number 16817-43-9
Molecular Formula C7H6BrClO
Molecular Weight 221.479 g/mol
Appearance Colorless to light yellow liquid or powder
Assay (Purity) ≥98.0%
Boiling Point 231.9±20.0 °C at 760 mmHg
Melting Point 27-28 °C
Density 1.6±0.1 g/cm3
Flash Point 94.1±21.8 °C

Industrial Applications

This halogenated anisole derivative is primarily utilized in the synthesis of fine chemicals and active pharmaceutical ingredients. Its dual halogen substitution offers versatile handles for cross-coupling reactions such as Suzuki, Heck, or Buchwald-Hartwig aminations. Consequently, it is frequently employed in the research and development of new therapeutic compounds targeting various biological pathways.

Beyond pharmaceuticals, this intermediate finds application in the agrochemical sector, where it contributes to the creation of novel pesticides and herbicides. The high purity level ensures minimal side reactions during synthesis, optimizing yield and reducing downstream purification costs. Our technical team supports clients with detailed documentation to facilitate seamless integration into existing manufacturing processes.

Storage and Handling

Proper storage is essential to maintain the integrity of 5-Bromo-2-chloroanisole. The product should be kept in a cool, ventilated area away from direct sunlight and moisture sources. Containers must remain tightly sealed when not in use to prevent oxidation or contamination. We recommend standard laboratory safety protocols, including the use of appropriate personal protective equipment during handling.

We offer flexible packaging options, including standard 25 kg drums, with customization available upon request to suit specific logistical requirements. Global shipping capabilities ensure timely delivery to research facilities and production plants worldwide. Contact our sales team for current bulk pricing, certificates of analysis, and technical data sheets.