Intermediates

5-Bromo-2-chloroisonicotinic acid

  • CAS No.886365-31-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 5-Bromo-2-chloroisonicotinic acid (CAS 886365-31-7) designed for complex organic synthesis. High purity ≥98.0% ensures reliable reaction outcomes for pharmaceutical intermediates.

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Product Technical Details

Product Overview

5-Bromo-2-chloroisonicotinic acid represents a critical building block in the realm of advanced organic synthesis and medicinal chemistry. As a halogenated pyridine derivative, this compound serves as a versatile intermediate for constructing complex molecular architectures. Our manufacturing process ensures that every batch meets rigorous international standards, providing researchers and industrial partners with a reliable foundation for drug discovery and development projects. The unique substitution pattern on the pyridine ring facilitates various cross-coupling reactions, making it an indispensable tool for synthetic chemists.

Key Specifications

We maintain strict quality control protocols to guarantee consistency across all production lots. The physical and chemical properties are meticulously verified to ensure optimal performance in downstream applications. Below are the detailed technical parameters for this product.

ParameterValue
Chemical Name5-Bromo-2-chloroisonicotinic acid
CAS Number886365-31-7
Molecular FormulaC6H3BrClNO2
Molecular Weight236.451 g/mol
AppearanceOff-white crystalline powder
Assay≥98.0%
Density1.9±0.1 g/cm3
Boiling Point419.3±45.0 °C at 760 mmHg
Flash Point207.4±28.7 °C

Industrial Applications

This specialized chemical intermediate is primarily utilized in the synthesis of pharmaceutical active ingredients and agrochemical compounds. The presence of both bromo and chloro substituents allows for selective functionalization, enabling chemists to introduce diverse functional groups at specific positions on the pyridine core. It is particularly valuable in the development of kinase inhibitors and other therapeutic agents where pyridine scaffolds are prevalent. Additionally, it serves as a key precursor in the manufacturing of specialty materials and fine chemicals requiring high structural precision.

Quality Assurance and Packaging

Our commitment to quality extends beyond mere specification compliance. Each production batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. We provide a Certificate of Analysis (COA) with every shipment to ensure full traceability and transparency. Standard packaging consists of 25 kg drums, which are designed to protect the material from moisture and physical damage during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements or smaller scale research needs.

Storage and Handling

To maintain stability and integrity, 5-Bromo-2-chloroisonicotinic acid should be stored in a cool, ventilated environment away from direct sunlight and sources of ignition. The container must be kept tightly closed when not in use to prevent exposure to atmospheric moisture. Personnel handling this material should adhere to standard laboratory safety practices, including the use of appropriate personal protective equipment such as gloves and safety goggles. Proper storage conditions ensure that the product retains its specified properties throughout its shelf life, supporting consistent results in your synthesis workflows.