Intermediates

(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

  • CAS No.461432-22-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone is a critical pharmaceutical intermediate used primarily in the synthesis of Empagliflozin, available with full COA.

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Product Technical Details

Product Overview

Welcome to our detailed specification page for (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone, a high-value organic compound identified by CAS number 461432-22-4. This specialized chemical serves as a fundamental building block within the pharmaceutical manufacturing sector. Our facility is dedicated to producing this intermediate with exceptional consistency and purity, ensuring it meets the rigorous demands of modern drug synthesis pipelines. As a key precursor, this molecule plays an indispensable role in the construction of complex therapeutic agents.

We understand that reliability in the supply chain is paramount for our B2B partners. Therefore, every batch undergoes strict analytical verification to confirm molecular integrity and structural accuracy. Our production capabilities allow us to support both pilot-scale research and large-scale commercial manufacturing requirements. By choosing our facility, you gain access to a stable supply of critical intermediates backed by decades of chemical engineering expertise.

Technical Specifications

Quality control is the cornerstone of our manufacturing process. The following table outlines the critical physical and chemical parameters for this product. We adhere to international standards to ensure that every shipment matches the specified profile.

ParameterSpecification
Chemical Name(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone
CAS Number461432-22-4
Molecular FormulaC15H12BrClO2
Molecular Weight339.61 g/mol
AppearanceWhite Powder
Purity>99.0%
Total Impurity≤0.5%
Water Content≤0.5%
Heavy Metals≤10 ppm
Boiling Point439.162°C at 760 mmHg
Density1.437 g/cm3

Quality Assurance

Our commitment to excellence extends beyond basic specification sheets. We implement a multi-stage quality assurance protocol that includes raw material screening, in-process monitoring, and final product validation. Advanced chromatographic techniques are employed to detect and quantify non-specific impurities, ensuring they remain below the 0.10% threshold. This level of precision is vital for downstream synthesis where impurity carryover can affect final drug safety.

  • Comprehensive Certificate of Analysis (COA) provided with every batch
  • Strict adherence to GMP standard operating procedures
  • Regular third-party auditing and validation
  • Traceability from raw materials to finished goods

Industrial Applications

The primary application of (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone is as a specialized intermediate in the synthesis of Empagliflozin. This compound facilitates specific chemical transformations required to build the active pharmaceutical ingredient. Its structural properties, including the bromo and chloro substituents, enable precise coupling reactions essential for maintaining the stereochemistry and efficacy of the final therapeutic product. Researchers and process chemists rely on this intermediate for its reactivity profile and stability during multi-step synthesis routes.

Storage and Handling

To maintain optimal quality, proper storage conditions are essential. This chemical should be stored in a well-closed container at low temperatures. It is imperative to keep the material away from moisture, excessive heat, and direct light sources. Exposure to humid environments can lead to hydrolysis or degradation, compromising the purity levels required for pharmaceutical use. Our packaging is designed to provide a robust barrier against environmental factors during transit and warehousing.

Packaging and Delivery

We offer flexible packaging solutions to accommodate various logistical needs. The standard packaging configuration is a 25kg cardboard drum, which ensures safety and ease of handling. For larger volume requirements, we can customize packaging according to customer specified requirements. Our global logistics network ensures timely delivery while maintaining the integrity of the chemical throughout the shipping process. Contact our sales team for detailed information on bulk pricing and lead times.