5-Bromo-2-Fluoro-3-Methylpyridine
- CAS No.29312-98-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Bromo-2-Fluoro-3-Methylpyridine (CAS 29312-98-9) designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
5-Bromo-2-Fluoro-3-Methylpyridine is a sophisticated halogenated heterocyclic compound that serves as a critical building block in modern organic chemistry. Characterized by its unique substitution pattern featuring both bromine and fluorine atoms on the pyridine ring, this molecule offers exceptional reactivity for cross-coupling reactions and nucleophilic substitutions. Our facility specializes in the production of this high-value intermediate, ensuring consistent quality for pharmaceutical and agrochemical research pipelines.
The strategic positioning of the fluoro and bromo substituents allows chemists to selectively functionalize the pyridine core. This versatility makes it an indispensable reagent for constructing complex molecular architectures required in next-generation therapeutic agents. We maintain rigorous production standards to guarantee that every batch meets the demanding specifications of global R&D laboratories.
Technical Specifications
Quality control is paramount in the supply of fine chemical intermediates. Our manufacturing process employs advanced purification techniques to achieve high assay values while minimizing impurities. The following table outlines the key physical and chemical parameters verified through our internal quality assurance protocols.
| Parameter | Specification |
|---|---|
| CAS Number | 29312-98-9 |
| Molecular Formula | C6H5BrFN |
| Molecular Weight | 190.01 g/mol |
| Appearance | White solid |
| Assay (Purity) | ≥98.0% |
| Moisture Content | ≤0.5% |
| Melting Point | 60-63°C |
| Boiling Point | 205.4°C |
| Density | 1.592 g/cm3 |
Industrial Applications
This fluorinated pyridine derivative is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). The presence of the carbon-fluorine bond often enhances metabolic stability and bioavailability in drug candidates, while the bromine atom facilitates palladium-catalyzed coupling reactions such as Suzuki, Heck, or Buchwald-Hartwig transformations.
Beyond pharmaceuticals, this compound finds application in the development of advanced agrochemicals and functional materials. Researchers leverage its chemical properties to introduce specific structural motifs that define the biological activity or physical characteristics of the final product. Our team supports clients with technical data to optimize the integration of this intermediate into their specific synthesis routes.
Quality Assurance and Handling
We understand that reliability in the supply chain is as crucial as product purity. Each production lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results against established specifications. Our packaging solutions are designed to maintain product integrity during transit, typically utilizing 25 kg drums or customized containers based on client requirements.
- Stored in a cool, ventilated environment to prevent degradation.
- Protected from moisture and direct sunlight during warehousing.
- Compatible with standard chemical handling safety protocols.
- Flash point monitored at 78°C for safe transportation classification.
As a global manufacturer, we are committed to providing consistent supply, competitive bulk pricing, and responsive technical support. Whether for scale-up projects or laboratory research, our 5-Bromo-2-Fluoro-3-Methylpyridine delivers the performance and reliability required for successful chemical synthesis.
