5-Bromo-2-Fluoro-4-Methylbenzaldehyde
- CAS No.497224-12-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Bromo-2-Fluoro-4-Methylbenzaldehyde (CAS 497224-12-1) is a premium fluorinated building block designed for efficient organic synthesis and pharmaceutical intermediate production.
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Product Overview
5-Bromo-2-Fluoro-4-Methylbenzaldehyde represents a critical fluorinated aromatic intermediate extensively utilized in modern organic synthesis and pharmaceutical development. This specialized chemical building block features a unique substitution pattern that enhances its reactivity profile, making it an indispensable precursor for the construction of complex molecular architectures. Our manufacturing process ensures exceptional batch-to-batch consistency, delivering a product that meets the rigorous demands of research laboratories and industrial production facilities alike.
The strategic placement of bromine, fluorine, and methyl groups on the benzaldehyde core provides chemists with versatile handles for further functionalization. This compound serves as a key starting material in the synthesis of advanced agrochemicals, novel pharmaceutical agents, and specialized functional materials. The high purity specification guarantees minimal side reactions during downstream processing, thereby optimizing yield and reducing purification costs for our partners.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 497224-12-1 |
| Molecular Formula | C8H6BrFO |
| Molecular Weight | 217.04 g/mol |
| Appearance | Off-white to white crystalline powder |
| Purity | ≥99.0% |
| Density | 1.575 g/cm3 |
| Boiling Point | 255.2 °C |
| Flash Point | 108.1 °C |
| Refractive Index | 1.575 |
Industrial Applications
As a versatile intermediate, this fluorinated benzaldehyde derivative finds extensive application across multiple high-value sectors. In the pharmaceutical industry, it acts as a crucial synthon for developing kinase inhibitors and other targeted therapies where fluorine substitution improves metabolic stability and bioavailability. The compound is also heavily employed in the agrochemical sector for synthesizing next-generation herbicides and fungicides that require specific electronic properties for optimal biological activity.
Furthermore, materials science researchers utilize this building block to create organic electronic components and liquid crystal displays. The presence of the halogen substituents facilitates cross-coupling reactions such as Suzuki, Heck, and Sonogashira protocols, enabling the rapid assembly of conjugated systems. Our global supply chain ensures that manufacturers receive timely deliveries to maintain uninterrupted production schedules.
Quality Assurance and Handling
We adhere to strict quality control protocols throughout the manufacturing lifecycle. Each batch undergoes comprehensive analysis using HPLC, GC-MS, and NMR spectroscopy to verify identity and purity levels. A Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. For safe handling, we recommend storing the material in a cool, well-ventilated area away from incompatible substances. Proper personal protective equipment should be worn during transfer operations to ensure workplace safety.
- Consistent high purity suitable for sensitive catalytic reactions
- Optimized packaging solutions including 25 kg drums or custom configurations
- Global logistics network ensuring reliable and timely delivery
- Technical support available for synthesis route optimization
- Competitive bulk pricing structures for long-term partnerships
