Intermediates

5-Bromo-2-fluoroaniline

  • CAS No.2924-09-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 5-Bromo-2-fluoroaniline (CAS 2924-09-6) designed for complex organic synthesis. High purity ≥98.0% ensures reliable reaction yields for pharmaceutical and agrochemical manufacturing.

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Product Technical Details

Product Overview

5-Bromo-2-fluoroaniline is a highly specialized halogenated aromatic amine that serves as a critical building block in modern organic chemistry. As a dual-substituted benzene derivative featuring both bromine and fluorine atoms, this compound offers unique reactivity profiles that are essential for the construction of complex molecular architectures. Our manufacturing process ensures exceptional consistency, making it an ideal choice for research and development teams as well as large-scale industrial production facilities.

The strategic placement of the fluoro and bromo substituents on the aniline ring provides versatile handles for further functionalization. This chemical is particularly valued in medicinal chemistry where fluorine incorporation can significantly enhance metabolic stability and bioavailability of potential drug candidates. We maintain rigorous quality control standards to guarantee that every batch meets the stringent requirements of downstream synthesis applications.

Technical Specifications

ParameterValue
Chemical Name5-Bromo-2-fluoroaniline
CAS Registry Number2924-09-6
Molecular FormulaC6H5BrFN
Molecular Weight190.013 g/mol
AppearanceYellow powder
Purity (Assay)≥98.0%
Density1.7±0.1 g/cm3
Boiling Point225.9±20.0 °C at 760 mmHg
Flash Point90.4±21.8 °C
Refractive Index1.597

Industrial Applications

This intermediate is extensively utilized in the synthesis of advanced pharmaceutical active ingredients (APIs). The presence of the bromine atom allows for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, while the fluorine atom contributes to favorable physicochemical properties in the final molecule. Beyond pharmaceuticals, this compound finds applications in the agrochemical sector for developing novel pesticides and herbicides with improved environmental profiles.

Materials science researchers also leverage this building block for creating specialized polymers and liquid crystals. The high purity level of our product minimizes side reactions during synthesis, thereby improving overall yield and reducing purification costs. Whether used in kilogram-scale pilot studies or multi-ton commercial production, our 5-Bromo-2-fluoroaniline delivers consistent performance.

Quality Assurance and Logistics

We understand that supply chain reliability is as crucial as product quality. Each production lot undergoes comprehensive analysis using advanced chromatographic and spectroscopic methods to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with international standards. Our packaging options include standard 25 kg drums, with flexibility to accommodate custom requirements based on specific customer needs.

Proper storage is essential to maintain product integrity. We recommend storing this chemical in a cool, ventilated area away from direct sunlight and moisture. Our global logistics network ensures timely delivery while adhering to all safety regulations for transporting chemical substances. Partner with us for a stable supply of high-performance chemical intermediates that drive your innovation forward.