5-Bromo-2-iodopyrimidine
- CAS No.183438-24-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade 5-Bromo-2-iodopyrimidine designed for pharmaceutical API synthesis, offering high purity and reliable supply for global manufacturing partners.
Request Bulk PricingProduct Technical Details
Product Overview
5-Bromo-2-iodopyrimidine is a highly specialized halogenated heterocyclic compound serving as a critical building block in modern pharmaceutical chemistry. As a key intermediate, it facilitates complex cross-coupling reactions essential for constructing advanced therapeutic molecules. Our manufacturing process ensures exceptional consistency and purity, meeting the rigorous demands of global API production facilities.
This compound is particularly valued for its reactivity profile, allowing chemists to selectively functionalize the pyrimidine ring at specific positions. The presence of both bromine and iodine substituents provides versatile handles for sequential coupling strategies, making it indispensable in the synthesis of targeted medicines.
Technical Specifications
We adhere to strict quality control protocols to guarantee product reliability. Each batch undergoes comprehensive analysis using HPLC and NMR spectroscopy to verify structural integrity and purity levels. The following table outlines the standard physical and chemical properties associated with this material.
| Parameter | Specification |
|---|---|
| CAS Number | 183438-24-6 |
| Molecular Formula | C4H2BrIN2 |
| Molecular Weight | 284.880 g/mol |
| Appearance | White to light yellow powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 99-103 °C |
| Density | 2.5±0.1 g/cm3 |
| Boiling Point | 341.0±34.0 °C |
Industrial Applications
The primary application of 5-Bromo-2-iodopyrimidine lies in the pharmaceutical sector, specifically as a precursor in the synthesis of Macitentan. This endothelin receptor antagonist is used in the treatment of pulmonary arterial hypertension, highlighting the critical role this intermediate plays in producing life-saving medications. Beyond this specific pathway, the compound is utilized in various research and development projects focused on kinase inhibitors and other heterocyclic drug candidates.
Our production capabilities support large-scale requirements while maintaining the precision needed for laboratory-scale optimization. We understand the importance of supply chain stability in pharmaceutical manufacturing and offer flexible packaging solutions to accommodate diverse operational needs.
Quality Assurance and Storage
To maintain optimal stability, this product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper handling procedures ensure that the chemical properties remain intact throughout the storage period. We provide a Certificate of Analysis (COA) with every shipment, documenting batch-specific test results to ensure compliance with agreed specifications.
- High purity levels suitable for GMP manufacturing environments.
- Robust packaging options including 25 kg drums or custom configurations.
- Global logistics support ensuring timely delivery to international clients.
- Dedicated technical support for synthesis route optimization.
Partner with us for a reliable supply of 5-Bromo-2-iodopyrimidine. Our commitment to quality, safety, and customer service makes us a preferred choice for pharmaceutical companies and chemical distributors worldwide.
