Intermediates

5-Bromo-2-methylpyridine

  • CAS No.3430-13-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Bromo-2-methylpyridine (CAS 3430-13-5) designed for advanced organic synthesis applications. Available in bulk quantities with strict quality control.

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Product Technical Details

Product Overview

5-Bromo-2-methylpyridine, also known commercially as 5-Bromo-2-picoline, is a highly valued heterocyclic compound serving as a critical building block in modern organic chemistry. Characterized by a pyridine ring substituted with a bromine atom at the fifth position and a methyl group at the second position, this chemical exhibits unique reactivity profiles suitable for various transformation reactions. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for downstream synthesis processes.

As a key precursor in medicinal chemistry and agrochemical development, this compound facilitates the construction of complex molecular architectures. The presence of the bromine substituent allows for versatile cross-coupling reactions, while the methyl group provides additional functionalization opportunities. We prioritize the delivery of materials that meet the rigorous demands of research laboratories and industrial production lines alike.

Technical Specifications

Our manufacturing process ensures that every batch of 5-Bromo-2-methylpyridine adheres to strict physicochemical parameters. The following table outlines the standard specifications for our premium grade product. Custom specifications may be available upon request for large-scale industrial partnerships.

ParameterSpecification
Chemical Name5-Bromo-2-methylpyridine
CAS Number3430-13-5
Molecular FormulaC6H6BrN
Molecular Weight172.023 g/mol
AppearanceLight yellow liquid
Assay (Purity)≥98.0%
Density1.5±0.1 g/cm3
Boiling Point182.7±20.0 °C at 760 mmHg
Melting Point32-36 °C
Flash Point64.3±21.8 °C
Refractive Index1.553

Industrial Applications

This brominated pyridine derivative is extensively utilized in the synthesis of pharmaceutical active ingredients and functional materials. Its primary utility lies in palladium-catalyzed coupling reactions, such as Suzuki-Miyaura and Heck reactions, which are fundamental in creating carbon-carbon bonds. Additionally, it serves as a vital intermediate in the production of agrochemicals, including herbicides and insecticides, where specific heterocyclic structures are required for biological activity.

  • Pharmaceutical intermediate for drug discovery programs.
  • Reagent for heterocyclic chemistry and ligand synthesis.
  • Component in the manufacturing of advanced agrochemical formulations.
  • Building block for functional materials and organic electronics.

Quality Assurance and Safety

We maintain a comprehensive quality assurance protocol that includes raw material screening, in-process monitoring, and final product verification. Each shipment is accompanied by a Certificate of Analysis (COA) to verify purity and identity. Regarding safety, 5-Bromo-2-methylpyridine should be handled with care. It is recommended to use appropriate personal protective equipment, including chemical-resistant gloves and safety goggles, during handling operations.

Storage requirements dictate keeping the container tightly closed in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents. Proper ventilation is essential to prevent the accumulation of vapors. In case of spills, absorb with inert material and dispose of according to local environmental regulations. Our technical support team is available to provide detailed Safety Data Sheets (SDS) and handling guidelines.

Logistics and Support

Understanding the importance of supply chain reliability, we offer flexible packaging solutions to meet diverse customer needs. The standard packaging configuration is 5 kg per drum, ensuring safe transport and ease of handling. However, we accommodate custom packaging requirements for bulk orders to optimize logistics efficiency. Our global distribution network ensures timely delivery to major chemical hubs worldwide.

Partnering with us provides access to consistent supply, competitive bulk pricing, and expert technical support. Whether for pilot-scale research or full-scale manufacturing, our commitment to quality and service makes us a preferred supplier for fine chemical intermediates. Contact our sales team today to discuss your specific requirements and request a quote.