5-Bromo-2-nitrobenzotrifluoride
- CAS No.344-38-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Bromo-2-nitrobenzotrifluoride (CAS 344-38-7) designed for advanced pharmaceutical and agrochemical synthesis workflows.
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Product Overview
5-Bromo-2-nitrobenzotrifluoride is a specialized fluorinated aromatic intermediate essential for modern organic synthesis. Characterized by its unique substitution pattern featuring bromine, nitro, and trifluoromethyl groups on a benzene ring, this compound serves as a versatile building block in the development of complex pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications.
As a key member of the halogenated nitrobenzene family, this material facilitates various coupling reactions and nucleophilic substitutions. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in downstream drug candidates, making it a preferred choice for medicinal chemists optimizing lead compounds.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 344-38-7 |
| Molecular Formula | C7H3BrF3NO2 |
| Molecular Weight | 270.00 g/mol |
| Appearance | Transparent yellow liquid |
| Purity | ≥98.0% |
| Density | 1.799 g/cm3 |
| Melting Point | 33-35 °C |
| Boiling Point | 95-100 °C at 5 mm Hg |
| Flash Point | >230 °F |
| Refractive Index | 1.522-1.524 |
Industrial Applications
This intermediate is primarily utilized in the synthesis of active pharmaceutical ingredients (APIs) where fluorinated structures are required to improve bioavailability. It acts as a critical precursor in the production of antibiotics, antifungals, and specialized kinase inhibitors. Additionally, the compound finds application in the agrochemical sector for developing herbicides and pesticides that require robust environmental stability.
- Pharmaceutical API synthesis and drug discovery
- Agrochemical formulation development
- Advanced organic synthesis research
- Custom chemical manufacturing projects
Quality and Safety
We adhere to strict quality control protocols to ensure every batch meets international standards. Each shipment is accompanied by a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). Proper handling procedures should be followed due to the nitro functionality. Store in a tightly closed container in a cool, dry environment away from incompatible materials. Our global logistics network ensures safe and timely delivery for bulk orders.
