Intermediates

5-Bromo-2-pyridinecarbonitrile

  • CAS No.97483-77-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Bromo-2-pyridinecarbonitrile (CAS 97483-77-7) is a crucial building block for pharmaceutical and agrochemical synthesis, available in bulk quantities with strict quality control.

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Product Technical Details

Product Overview

5-Bromo-2-pyridinecarbonitrile is a highly valued heterocyclic compound widely utilized in the field of advanced organic synthesis. As a key intermediate, this chemical features a pyridine ring substituted with both bromo and nitrile functional groups, providing versatile reactivity for downstream chemical transformations. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and industrial scale applications.

The presence of the bromine atom at the fifth position and the cyano group at the second position of the pyridine ring allows for diverse coupling reactions. This molecular structure facilitates nucleophilic substitution and cross-coupling processes, which are essential in constructing complex molecular architectures found in modern medicinal chemistry and material science.

Key Specifications

ParameterValue
CAS Number97483-77-7
Molecular FormulaC6H3BrN2
Molecular Weight183.005
AppearanceOff-white to light yellow crystalline powder
Assay≥98.0%
Melting Point128-132 °C
Boiling Point260.3±20.0 °C at 760 mmHg
Density1.7±0.1 g/cm3

Industrial Applications

This compound serves as a fundamental building block in the synthesis of various pharmaceutical agents. Its structural properties enable chemists to introduce nitrogen-containing heterocycles into drug candidates, enhancing biological activity and metabolic stability. Additionally, it is frequently employed in the development of agrochemicals, where pyridine derivatives play a critical role in pest control and plant growth regulation.

Beyond pharmaceuticals and agrochemicals, 5-Bromo-2-pyridinecarbonitrile is utilized in the production of specialty polymers and organic materials. The nitrile group offers potential for further functionalization into amides, amines, or tetrazoles, expanding its utility in material science applications. Our global clientele relies on this intermediate for creating high-performance compounds with specific electronic or chemical properties.

Quality Assurance and Storage

We adhere to strict quality management systems to guarantee the integrity of every batch. Each production lot undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR to verify purity and structural confirmation. A Certificate of Analysis (COA) is provided with every shipment, ensuring transparency and compliance with international standards.

  • Consistent batch-to-batch reproducibility
  • Low impurity profile suitable for sensitive reactions
  • Comprehensive documentation and regulatory support

For optimal stability, this product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper packaging in sealed drums ensures protection during transit and storage. We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom requirements based on specific logistical needs. Contact our sales team for detailed information on bulk pricing, lead times, and shipping arrangements to support your production schedule.