5-Bromo-3-nitropicolinonitrile
- CAS No.573675-25-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Bromo-3-nitropicolinonitrile (CAS 573675-25-9) designed for advanced organic synthesis and pharmaceutical intermediate applications.
Request Bulk PricingProduct Technical Details
Product Overview
5-Bromo-3-nitropicolinonitrile is a highly specialized heterocyclic compound recognized for its significant utility in modern organic synthesis. As a functionalized pyridine derivative, this chemical serves as a critical building block for the development of complex pharmaceutical agents and agrochemical formulations. The presence of both bromo and nitro substituents on the pyridine ring provides versatile reactivity profiles, enabling chemists to perform various nucleophilic substitutions and cross-coupling reactions with high efficiency.
Our manufacturing facility ensures that every batch of 5-Bromo-3-nitropicolinonitrile meets stringent quality standards suitable for research and industrial scale-up. The compound is characterized by its stability under standard storage conditions and its compatibility with a wide range of synthetic pathways. Whether utilized in the early stages of drug discovery or in the optimization of production processes, this intermediate offers reliable performance and consistency.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 573675-25-9 |
| Molecular Formula | C6H2BrN3O2 |
| Molecular Weight | 228.003 |
| Appearance | Yellow crystalline powder |
| Assay | ≥98.0% |
| Moisture | ≤0.5% |
| Melting Point | 101-106ºC |
| Density | 1.9±0.1 g/cm3 |
| Boiling Point | 348.9±42.0 ºC at 760 mmHg |
Industrial Applications
The primary application of 5-Bromo-3-nitropicolinonitrile lies in the synthesis of advanced organic molecules. The electron-withdrawing nature of the nitro and cyano groups activates the pyridine ring, facilitating selective transformations. This makes it an invaluable precursor in the pharmaceutical industry for constructing kinase inhibitors, antiviral agents, and other therapeutic compounds. Additionally, it finds usage in the agrochemical sector for developing novel pesticides and herbicides that require specific heterocyclic scaffolds.
Researchers value this intermediate for its ability to undergo palladium-catalyzed coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, allowing for the introduction of diverse functional groups. Its robust chemical structure ensures that it withstands rigorous reaction conditions while maintaining integrity, leading to higher yields and purer final products in multi-step synthesis routes.
Quality Assurance and Storage
- Quality Control: Each production lot undergoes rigorous testing using HPLC and NMR to verify identity and purity levels.
- Packaging: Standard packaging includes 25 kg drums, with customizable options available to meet specific logistical requirements.
- Storage Conditions: To maintain optimal stability, store in a cool, ventilated place away from direct sunlight and moisture sources.
- Documentation: Comprehensive Certificates of Analysis (COA) and safety data sheets are provided with every shipment.
- Global Logistics: We offer reliable shipping solutions to ensure timely delivery to laboratories and manufacturing plants worldwide.
Partnering with us ensures access to premium chemical intermediates backed by decades of industry expertise. Our commitment to quality and customer support makes us a preferred supplier for businesses seeking scalable and compliant chemical solutions.
