Intermediates

5-Bromo-3-(Trifluoromethyl)-2-Pyridinecarbonitrile

  • CAS No.1214377-57-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Bromo-3-(Trifluoromethyl)-2-Pyridinecarbonitrile is a specialized fluorinated heterocyclic intermediate designed for advanced pharmaceutical synthesis and organic chemistry applications.

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Product Technical Details

Product Overview

5-Bromo-3-(Trifluoromethyl)-2-Pyridinecarbonitrile represents a critical building block in the realm of modern medicinal chemistry and organic synthesis. As a fluorinated pyridine derivative, this compound offers unique reactivity profiles that are essential for constructing complex molecular architectures found in next-generation therapeutic agents. Our manufacturing process ensures exceptional consistency and quality, making it an ideal choice for research and development teams focused on drug discovery.

This specialized intermediate features a robust pyridine core substituted with both bromo and trifluoromethyl groups, providing versatile sites for cross-coupling reactions and nucleophilic substitutions. The presence of the nitrile functionality further expands its utility in synthesizing diverse heterocyclic systems. We prioritize strict quality control measures to deliver material that meets the rigorous demands of pharmaceutical industrial applications.

Key Specifications

ParameterSpecification
Chemical Name5-Bromo-3-(Trifluoromethyl)-2-Pyridinecarbonitrile
CAS Number1214377-57-7
Molecular FormulaC7H2BrF3N2
Molecular Weight251.00 g/mol
AppearanceWhite Crystalline Powder
Purity≥99.0%
Boiling Point257°C
Density1.81 g/cm3
Flash Point110°C

Industrial Applications

Primarily utilized as a pharmaceutical intermediate, this compound serves as a foundational element in the synthesis of active pharmaceutical ingredients (APIs). Its structural characteristics enable chemists to introduce specific fluorinated motifs into drug candidates, which can significantly enhance metabolic stability and bioavailability. The bromine atom facilitates palladium-catalyzed coupling reactions, while the trifluoromethyl group imparts desirable lipophilic properties.

Beyond pharmaceuticals, this chemical finds relevance in the development of agrochemicals and advanced materials where fluorinated heterocycles are required. Our global supply chain supports large-scale production needs, ensuring that clients receive timely deliveries accompanied by comprehensive documentation, including Certificates of Analysis (COA) and safety data sheets.

Quality Assurance and Storage

We adhere to international standards for chemical manufacturing to guarantee product integrity. Each batch undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR to confirm identity and purity levels. To maintain optimal stability, the product should be stored in a tightly closed container within a cool, dry environment, protected from moisture and direct sunlight. Proper handling procedures are recommended to ensure safety during laboratory or industrial use.

  • High purity levels suitable for sensitive synthetic routes
  • Consistent batch-to-batch reproducibility
  • Supported by comprehensive technical documentation
  • Available in bulk quantities for industrial scaling