Intermediates

5-Bromo-6-Methoxypyridin-3-Amine

  • CAS No.53242-18-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Bromo-6-Methoxypyridin-3-Amine intermediate designed for advanced organic synthesis and pharmaceutical research applications.

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Product Technical Details

Product Overview

5-Bromo-6-Methoxypyridin-3-Amine represents a critical building block in the realm of modern medicinal chemistry and organic synthesis. As a specialized pyridine derivative, this compound features a unique substitution pattern that includes both a bromine atom and a methoxy group on the pyridine ring. This specific structural arrangement provides chemists with versatile reactive sites, making it an invaluable precursor for the development of complex molecular architectures. Our facility is dedicated to supplying this high-quality intermediate to research institutions and industrial partners worldwide.

The significance of this compound lies in its utility as a key intermediate for constructing biologically active molecules. The bromine substituent serves as an excellent handle for palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, or Buchwald-Hartwig couplings. Meanwhile, the methoxy group influences the electronic properties of the ring, allowing for fine-tuned reactivity in downstream synthesis steps. This combination makes it a preferred choice for scientists working on novel pharmaceutical agents and agrochemical formulations.

Technical Specifications

We adhere to strict quality control protocols to ensure every batch meets the highest standards of purity and consistency. Our analytical teams utilize advanced high-performance liquid chromatography (HPLC) techniques to verify composition. The physical properties are consistent with theoretical values, ensuring reliable performance in your synthesis workflows. Below are the detailed specifications for this product:

ParameterValue
CAS Number53242-18-5
Molecular FormulaC6H7BrN2O
Molecular Weight203.04 g/mol
Purity (HPLC)≥98.0%
AppearanceBrown Solid
Density1.622 g/cm3
Boiling Point292.4 °C
Flash Point130.7 °C
Refractive Index1.602

Industrial Applications

This chemical is primarily utilized as an intermediate in the synthesis of complex organic compounds. Its applications span across several key sectors within the chemical industry. In pharmaceutical research, it serves as a core structure for developing new therapeutic candidates targeting various biological pathways. The stability of the pyridine ring combined with the reactivity of the substituents allows for diverse chemical transformations.

  • Pharmaceutical Intermediate: Used in the multi-step synthesis of active pharmaceutical ingredients (APIs).
  • Agrochemical Development: Employed in the creation of novel pesticides and herbicides.
  • Material Science: Utilized in the synthesis of specialized polymers and functional materials.
  • Research and Development: Essential for academic and industrial labs focusing on heterocyclic chemistry.

Quality Assurance and Packaging

Quality is the cornerstone of our manufacturing process. Each production batch undergoes rigorous testing to confirm identity and purity levels. We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for your quality records. Our commitment to excellence ensures that you receive materials that perform consistently in your processes.

Regarding logistics, we offer flexible packaging solutions to meet your operational needs. The standard packaging is 25 kg per drum, which ensures safety and ease of handling during transport. However, we understand that different projects have different requirements. Therefore, we can also customize packaging according to specific customer requests. Storage recommendations include keeping the product in a cool, ventilated place away from direct sunlight and moisture to maintain stability over time. Contact our sales team today for bulk pricing and availability.