Intermediates

5-Bromopyridine-3-carbonitrile

  • CAS No.35590-37-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Bromopyridine-3-carbonitrile (CAS 35590-37-5) designed for advanced organic synthesis and pharmaceutical intermediate applications.

Request Bulk Pricing

Product Technical Details

Product Overview

5-Bromopyridine-3-carbonitrile is a highly valued heterocyclic building block extensively utilized in modern organic synthesis and medicinal chemistry. As a functionalized pyridine derivative, this compound features both a bromine substituent and a nitrile group, offering versatile reactivity for complex molecular construction. Our manufacturing process ensures exceptional purity levels, making it an ideal candidate for developing advanced pharmaceutical agents, agrochemicals, and specialized functional materials.

We understand the critical nature of supply chain consistency in the chemical industry. Therefore, every batch of 5-Bromopyridine-3-carbonitrile undergoes rigorous quality control protocols. Our facility employs state-of-the-art analytical instrumentation, including High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy, to verify chemical identity and purity standards before shipment. This commitment to quality assurance guarantees that researchers and production teams receive materials that meet stringent specifications for reproducible results.

Technical Specifications

ParameterSpecification
CAS Number35590-37-5
Molecular FormulaC6H3BrN2
Molecular Weight183.005 g/mol
AppearanceOff-white solid
Assay (Purity)≥98.0%
Moisture Content≤0.5%
Melting Point103-107 °C
Boiling Point228.8±20.0 °C at 760 mmHg
Density1.7±0.1 g/cm3

Industrial Applications

The unique structural properties of this brominated pyridine derivative enable its use in a wide array of synthetic transformations. It serves as a crucial intermediate in cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig couplings, facilitating the formation of carbon-carbon and carbon-nitrogen bonds. The presence of the cyano group allows for further functionalization through hydrolysis or reduction, expanding its utility in creating diverse chemical libraries.

  • Pharmaceutical Intermediate: Essential for synthesizing kinase inhibitors and other therapeutic molecules.
  • Agrochemical Synthesis: Used in the development of novel pesticides and herbicides.
  • Material Science: Applied in the creation of organic electronic materials and polymers.
  • Research and Development: A standard reagent for academic and industrial laboratory investigations.

Storage and Handling

To maintain optimal stability and performance, 5-Bromopyridine-3-carbonitrile should be stored in a cool, dry, and well-ventilated area away from direct sunlight and moisture. The material is packaged in secure 25 kg drums, though we offer flexible packaging solutions tailored to specific customer requirements. Proper handling procedures, including the use of personal protective equipment, are recommended during transfer and processing to ensure safety compliance. Our logistics team ensures global shipping capabilities with full documentation, including Certificates of Analysis (COA) and Safety Data Sheets (SDS), to support seamless integration into your manufacturing workflow.