5-Bromopyrimidine
- CAS No.4595-59-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 5-Bromopyrimidine (CAS 4595-59-9) designed for agrochemical synthesis. Reliable supply with comprehensive quality documentation for industrial scaling.
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Product Overview
5-Bromopyrimidine stands as a pivotal heterocyclic compound within the realm of advanced organic synthesis. As a halogenated pyrimidine derivative, this chemical serves as an essential building block for the construction of complex molecular architectures. Our facility specializes in the production of this intermediate with a focus on consistent quality and high purity standards suitable for demanding industrial applications.
The presence of the bromine atom at the fifth position of the pyrimidine ring provides significant reactivity, making it an ideal candidate for cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. This versatility allows chemists to introduce various functional groups efficiently, facilitating the development of novel agrochemicals and pharmaceutical candidates.
Physical and Chemical Properties
Understanding the physicochemical characteristics of 5-Bromopyrimidine is crucial for safe handling and effective utilization in synthesis protocols. The compound exhibits stable properties under standard storage conditions while maintaining high reactivity during chemical transformations. Below are the key specifications verified through our rigorous quality control processes.
| Property | Specification |
|---|---|
| CAS Number | 4595-59-9 |
| Molecular Formula | C4H3BrN2 |
| Molecular Weight | 158.984 g/mol |
| Appearance | Light yellow powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 69 °C |
| Boiling Point | 201.4±13.0 °C at 760 mmHg |
| Density | 1.7±0.1 g/cm3 |
| Flash Point | 75.6±19.8 °C |
| Vapour Pressure | 0.4±0.4 mmHg at 25°C |
| Index of Refraction | 1.568 |
Industrial Applications
The primary application of 5-Bromopyrimidine lies in the synthesis of agrochemical active ingredients. Notably, it serves as a critical intermediate in the manufacturing process of Flurprimidol, a well-known plant growth regulator. The high purity of our supplied material ensures optimal reaction yields and minimizes the formation of unwanted by-products during downstream processing.
Beyond agrochemicals, this compound finds utility in medicinal chemistry research where pyrimidine scaffolds are prevalent. It is frequently employed in the development of kinase inhibitors and other therapeutic agents targeting neurological or metabolic pathways. Our manufacturing process is designed to support both large-scale production runs and custom synthesis requirements for research and development teams.
Quality Assurance and Storage
We adhere to strict quality management systems to guarantee the integrity of every batch. Each shipment is accompanied by a Certificate of Analysis (COA) detailing the test results against specified parameters. Our commitment to industrial purity means that customers can rely on consistent performance across multiple production cycles.
For optimal preservation, 5-Bromopyrimidine should be stored in a cool, ventilated place away from direct sunlight and moisture. The packaging consists of 25 kg drums, though we offer flexible packaging solutions tailored to specific customer logistics requirements. Proper handling procedures should be followed to maintain safety standards in the laboratory or production facility.
