Intermediates

5-Bromovaleryl Chloride

  • CAS No.4509-90-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 5-Bromovaleryl Chloride (CAS 4509-90-4) designed for advanced organic synthesis and pharmaceutical intermediate applications. Available in bulk quantities with comprehensive COA.

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Product Technical Details

Product Overview

5-Bromovaleryl Chloride is a highly reactive acyl chloride derivative that serves as a critical building block in modern organic chemistry. Characterized by its bromine substitution at the terminal position of the valeryl chain, this compound offers unique reactivity profiles suitable for nucleophilic acyl substitution reactions. It is extensively utilized in the development of complex molecular structures within the pharmaceutical and fine chemical sectors. Our grade ensures consistent performance in sensitive synthesis pathways, providing researchers and industrial manufacturers with a reliable source for downstream processing.

The chemical stability and purity of this reagent are paramount for ensuring high yields in subsequent reaction steps. We employ advanced distillation and purification techniques to minimize impurities such as free acids or unreacted starting materials. This commitment to quality makes our 5-Bromovaleryl Chloride an ideal choice for scaling up from laboratory research to commercial production environments.

Technical Specifications

ParameterSpecification
CAS Number4509-90-4
Molecular FormulaC5H8BrClO
Molecular Weight199.47 g/mol
AppearanceClear colorless to pale yellow liquid
Purity≥96.0%
Density1.49 g/mL at 25 °C
Boiling Point116-118 °C at 33 mm Hg
Refractive Indexn20/D 1.492
Moisture Content≤0.2%
Total Impurities≤0.5%

Industrial Applications

This compound is primarily employed as a key intermediate in the synthesis of pharmaceutical agents and agrochemicals. Its bifunctional nature, containing both an acyl chloride group and a bromoalkyl chain, allows for versatile chemical transformations. Common applications include the formation of amides, esters, and ketones through reactions with amines, alcohols, or organometallic reagents. Additionally, it serves as a precursor in the construction of heterocyclic systems found in various therapeutic classes.

In the context of industrial manufacturing, 5-Bromovaleryl Chloride facilitates the efficient introduction of five-carbon chains with functional handles for further modification. This capability is essential for optimizing synthetic routes, reducing step counts, and improving overall process economics. Our supply chain supports large-scale procurement needs, ensuring continuity for production lines dependent on this specific reagent.

Quality Assurance

Every batch of 5-Bromovaleryl Chloride undergoes rigorous quality control testing before release. We utilize gas chromatography (GC) and nuclear magnetic resonance (NMR) spectroscopy to verify identity and purity levels. A Certificate of Analysis (COA) is provided with each shipment, detailing specific test results against our internal specifications. This transparency allows our clients to maintain their own quality standards without additional incoming inspection delays.

Safety and Storage

As a corrosive and moisture-sensitive substance, proper handling procedures are essential. Personnel should wear appropriate personal protective equipment, including chemical-resistant gloves, safety goggles, and lab coats. The material must be stored in a tightly closed container within a cool, dry, and well-ventilated area, segregated from incompatible substances such as strong oxidizers, bases, and water. In case of spills, neutralize with appropriate agents and absorb with inert material before disposal according to local regulations.