5-Chloro-2-Fluoro-4-Iodopyridine
- CAS No.659731-48-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Chloro-2-Fluoro-4-Iodopyridine (CAS 659731-48-3) designed for pharmaceutical synthesis. Reliable supply with ≥98.0% purity for advanced organic chemistry applications.
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Product Overview
Our premium 5-Chloro-2-Fluoro-4-Iodopyridine is a highly specialized halogenated heterocyclic compound designed for advanced organic synthesis and medicinal chemistry applications. As a critical building block, this fluorinated pyridine derivative offers exceptional reactivity profiles due to the strategic positioning of chloro, fluoro, and iodo substituents on the pyridine ring. This unique arrangement facilitates selective cross-coupling reactions, making it an indispensable resource for researchers and industrial manufacturers developing novel pharmaceutical agents and agrochemical solutions.
We understand the stringent requirements of modern chemical synthesis. Therefore, our production process adheres to rigorous quality control standards to ensure consistent batch-to-batch reliability. Each lot is thoroughly analyzed to confirm structural integrity and purity levels, providing our global partners with the confidence needed for scale-up operations and complex multi-step synthesis routes. The incorporation of fluorine atoms is particularly valued in drug design for enhancing metabolic stability, while the iodine moiety serves as an excellent handle for palladium-catalyzed coupling reactions.
Key Specifications
The following technical parameters define the quality standards of our 5-Chloro-2-Fluoro-4-Iodopyridine supply. We maintain tight controls over physical and chemical properties to meet the demands of high-precision laboratory and industrial environments. Our analytical teams utilize advanced chromatography and spectroscopy methods to verify every shipment.
| Parameter | Specification |
|---|---|
| Chemical Name | 5-Chloro-2-Fluoro-4-Iodopyridine |
| CAS Number | 659731-48-3 |
| Molecular Formula | C5H2ClFIN |
| Molecular Weight | 257.43 g/mol |
| Appearance | White to light yellow crystal powder |
| Purity | ≥98.0% |
| Boiling Point | 250.8±35.0 °C at 760 mmHg |
| Density | 2.1±0.1 g/cm3 |
| Flash Point | 105.5±25.9 °C |
Industrial Applications
This versatile intermediate serves as a foundational component in the synthesis of complex organic molecules. Its primary utility lies in the pharmaceutical sector, where halogenated pyridines are frequently employed to construct active pharmaceutical ingredients (APIs). The presence of multiple halogen atoms allows for sequential functionalization, enabling chemists to introduce diverse structural motifs efficiently without compromising the core scaffold stability.
- Medicinal Chemistry: Used as a core scaffold for developing new therapeutic compounds and kinase inhibitors.
- Agrochemical Synthesis: Applied in the creation of advanced crop protection agents and herbicides.
- Material Science: Utilized in the development of specialized organic materials, ligands, and electronic chemicals.
- Custom Synthesis: Suitable for bespoke research projects requiring high-purity heterocyclic building blocks and precise stoichiometry.
Quality Assurance and Handling
Safety and stability are paramount in handling reactive chemical intermediates. Our 5-Chloro-2-Fluoro-4-Iodopyridine is packaged in secure 25 KGS drums to prevent contamination and moisture exposure during transit. We recommend storing the product in a tightly closed container within a cool, dry environment to maintain optimal stability over time. Proper ventilation and standard personal protective equipment should be used during handling procedures.
As a committed global manufacturer, we provide comprehensive documentation including Certificates of Analysis (COA) with every shipment. Our technical support team is available to assist with application guidance, ensuring seamless integration into your existing manufacturing processes. Partner with us for reliable supply chains, competitive bulk pricing, and uncompromising quality in every gram delivered. We are dedicated to supporting your innovation through consistent supply of high-performance chemical intermediates.
