Intermediates

5-Chloro-2-fluoropyridine

  • CAS No.1480-65-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Chloro-2-fluoropyridine (CAS 1480-65-5) designed for advanced pharmaceutical synthesis. Reliable supply with strict quality control for global industrial applications.

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Product Technical Details

Product Overview

5-Chloro-2-fluoropyridine is a highly valued heterocyclic compound extensively utilized in the field of organic synthesis and pharmaceutical manufacturing. As a halogenated pyridine derivative, this chemical serves as a critical building block for the development of advanced medicinal agents and agrochemical products. Our facility ensures that every batch meets rigorous international standards, providing researchers and industrial partners with a reliable source of high-purity intermediates.

The unique substitution pattern of chlorine and fluorine atoms on the pyridine ring offers versatile reactivity, enabling chemists to perform selective nucleophilic substitutions and cross-coupling reactions. This flexibility makes it an indispensable tool in the synthesis of complex molecular structures required for modern therapeutics. We prioritize consistency and safety in every production run to support your research and development goals.

Key Specifications

ParameterValue
Chemical Name5-Chloro-2-fluoropyridine
CAS Number1480-65-5
Molecular FormulaC5H3ClFN
Molecular Weight131.54 g/mol
AppearanceColorless to brown liquid
Purity≥98.0%
Boiling Point158.0±20.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point49.3±21.8 °C
Refractive Index1.503

Industrial Applications

This compound is primarily employed as a pharmaceutical intermediate, facilitating the construction of active pharmaceutical ingredients (APIs). Its stability and reactivity profile support various synthetic pathways, including Suzuki coupling and nucleophilic aromatic substitution. The presence of both chloro and fluoro substituents allows for differentiated functionalization, which is crucial in multi-step synthesis routes.

  • Pharmaceutical synthesis for novel drug candidates and therapeutic agents.
  • Agrochemical development for crop protection agents and pesticides.
  • Material science research involving functionalized heterocycles and polymers.
  • Custom organic synthesis projects requiring halogenated precursors.
  • Academic research focused on heterocyclic chemistry and reaction mechanisms.

Quality Assurance and Storage

We maintain strict quality control protocols throughout the manufacturing process. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified parameters. Our laboratory testing ensures that impurities are kept to minimal levels, safeguarding the integrity of your downstream processes. To maintain stability, the product should be stored in a tightly closed container within a cool, dry environment, away from incompatible materials and sources of ignition.

Our commitment to safety and quality ensures that clients receive materials suitable for sensitive research and large-scale production. Proper handling procedures should be followed according to standard safety data sheets. For bulk orders and technical inquiries, our team provides comprehensive support to meet your specific project requirements. We offer flexible packaging options, including 25 kg drums, to accommodate various logistical needs.

Partnering with us means accessing a global supply chain dedicated to excellence. We understand the critical nature of timely delivery in the chemical industry and strive to maintain optimal inventory levels. Contact our sales team today to discuss your specific purity requirements and obtain competitive pricing for your next project.