Intermediates

5-Chloro-3H-1,3-benzoxazole-2-thione

  • CAS No.22876-19-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Chloro-3H-1,3-benzoxazole-2-thione (CAS 22876-19-3) designed for pharmaceutical synthesis. Reliable supply with ≥99.0% purity for global research and manufacturing needs.

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Product Technical Details

Product Overview

5-Chloro-3H-1,3-benzoxazole-2-thione is a high-value heterocyclic compound extensively utilized in the field of medicinal chemistry and organic synthesis. As a critical building block, this chemical serves as a foundational intermediate for the development of advanced pharmaceutical agents. Our manufacturing process ensures exceptional molecular stability and consistency, making it an ideal choice for research laboratories and large-scale production facilities focused on neurological therapeutics and complex organic structures.

We understand the stringent requirements of the pharmaceutical industry. Therefore, every batch undergoes rigorous quality control testing to verify identity, purity, and physical properties. This commitment to excellence ensures that our clients receive materials that meet the highest international standards for chemical intermediates.

Physical and Chemical Properties

The molecular structure of this benzoxazole derivative contributes to its unique reactivity and stability profile. With a molecular formula of C7H4ClNOS and a molecular weight of 185.63 g/mol, it exhibits specific thermal and physical characteristics essential for downstream synthesis processes. Understanding these properties is vital for chemists planning reaction pathways involving thiol or thione functional groups.

PropertyValue
Molecular FormulaC7H4ClNOS
Molecular Weight185.63 g/mol
Density1.57 g/cm3
Boiling Point278.7ºC at 760mmHg
Melting Point280-285 ºC
Flash Point122.4ºC
Refractive Index1.723

Quality Specifications

Our production facility adheres to strict quality management systems. The following specifications represent the standard grade available for immediate shipment. Custom purity levels may be discussed for specific project requirements.

ParameterSpecification
AppearancePale Yellow Solid
Purity (HPLC)≥99.0%
Sulfated Ash0.01% Max
Heavy Metals10ppm Max
Total Impurity0.5% Max

Industrial Applications

This compound is primarily employed as a key intermediate in the synthesis of complex pharmaceutical APIs. It plays a significant role in the construction of benzoxazole-based scaffolds, which are prevalent in modern drug discovery programs targeting various therapeutic areas. Specifically, it is utilized in the manufacturing process of agents designed for neurological applications. Researchers value this material for its reliable performance in coupling reactions and heterocyclic modifications.

Storage and Handling

To maintain optimal quality, 5-Chloro-3H-1,3-benzoxazole-2-thione should be stored in a tightly closed container. The storage environment must be cool, dry, and well-ventilated, away from incompatible substances such as strong oxidizing agents. Proper handling procedures, including the use of personal protective equipment, are recommended during transfer and weighing operations to ensure safety.

Why Choose Our Supply

As a global manufacturer, we provide comprehensive support including detailed Certificates of Analysis (COA) with every shipment. Our logistics network ensures timely delivery worldwide, accommodating various packing requirements from standard 25kg cardboard drums to customized bulk solutions. Partner with us for reliable supply chains, competitive bulk pricing, and technical expertise in fine chemical intermediates.