Intermediates

5-Chloroethyl-6-Chloro-1,3-Dihydro-2H-Indole-2-One

  • CAS No.118289-55-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity pharmaceutical intermediate essential for the synthesis of Ziprasidone hydrochloride, available in bulk quantities with comprehensive quality documentation.

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Product Technical Details

Product Overview

5-Chloroethyl-6-Chloro-1,3-Dihydro-2H-Indole-2-One is a specialized organic compound widely recognized within the pharmaceutical industry as a critical building block. This chemical entity serves as a key precursor in the multi-step synthesis of advanced therapeutic agents, specifically functioning as an intermediate for Ziprasidone hydrochloride. Our manufacturing process ensures that each batch meets rigorous international standards for chemical purity and structural integrity, making it an ideal choice for large-scale pharmaceutical production.

The molecular structure features a chloroethyl side chain attached to a chlorinated indole core, which provides the necessary reactivity for downstream coupling reactions. This specific configuration is vital for maintaining the stereochemical requirements of the final active pharmaceutical ingredient. We prioritize consistency in every production run to support seamless integration into your existing synthesis workflows.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates. Our facility employs advanced analytical techniques including HPLC and NMR to verify composition. The following table outlines the standard specification parameters for this product:

ParameterSpecification
CAS Number118289-55-7
Molecular FormulaC10H9Cl2NO
Molecular Weight230.09 g/mol
AppearancePink to off-white solid
Purity≥99.0%
Loss on Drying≤1.0%
Maximum Impurity≤0.5%

Industrial Applications

This compound is primarily utilized in the medicinal chemistry sector for the construction of antipsychotic medications. Its role as a Ziprasidone intermediate highlights its importance in neurological therapeutic development. The high level of purity ensures minimal byproduct formation during subsequent reaction steps, thereby optimizing overall yield and reducing purification costs for downstream processors.

Beyond its primary application, this oxindole derivative may serve as a versatile scaffold in organic synthesis research. Chemical developers value its stability and reactivity profile for creating novel analogues. We support both standard commercial orders and custom synthesis projects tailored to specific research requirements.

Quality Assurance and Storage

To maintain product stability, proper handling protocols must be observed. The material should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is essential to keep the substance away from incompatible materials such as strong oxidizing agents. Our packaging options include 25kg cardboard drums or customized solutions based on client logistics needs.

  • Comprehensive Certificate of Analysis (COA) provided with every shipment.
  • Strict adherence to Good Manufacturing Practices (GMP) guidelines.
  • Global shipping capabilities with secure packaging to prevent moisture exposure.
  • Dedicated technical support for synthesis route optimization.

We are committed to supplying reliable chemical intermediates that empower pharmaceutical innovation. Contact our sales team for current bulk pricing and availability.