Intermediates

5-Chlorothiophene-2-carbonyl chloride

  • CAS No.42518-98-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Chlorothiophene-2-carbonyl chloride (CAS 42518-98-9) designed for pharmaceutical synthesis. Reliable supply with strict quality control for global manufacturing needs.

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Product Technical Details

Product Overview

5-Chlorothiophene-2-carbonyl chloride is a highly specialized organic intermediate essential for the synthesis of complex pharmaceutical compounds. Identified by CAS number 42518-98-9, this heterocyclic acyl chloride serves as a critical building block in modern medicinal chemistry. Our manufacturing process ensures exceptional purity levels, making it suitable for demanding synthetic routes where consistency and reliability are paramount. As a key component in the production of advanced therapeutic agents, this compound underscores our commitment to supplying high-quality chemical materials to the global pharmaceutical industry.

Technical Specifications

ParameterValue
Chemical Name5-Chlorothiophene-2-carbonyl chloride
CAS Number42518-98-9
Molecular FormulaC5H2Cl2OS
Molecular Weight181.040 g/mol
AppearanceLight yellow powder or liquid
Assay≥98.0%
Density1.5±0.1 g/cm3
Boiling Point223.9±20.0 °C at 760 mmHg
Flash Point89.2±21.8 °C

Industrial Applications

This compound is primarily utilized as a vital intermediate in the synthesis of anticoagulant medications, including pathways related to Rivaroxaban production. The thiophene ring structure provides unique chemical stability and reactivity, allowing for efficient coupling reactions in multi-step synthesis protocols. Pharmaceutical manufacturers rely on this reagent for its predictable performance in acylation reactions, ensuring high yields and minimal byproduct formation. Our supply chain supports large-scale production requirements, facilitating seamless integration into your existing manufacturing processes.

Quality Assurance and Handling

We adhere to strict quality control standards to guarantee the integrity of every batch. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying purity and physical properties. Proper handling is essential due to the reactive nature of acyl chlorides. We recommend storage in a cool, ventilated area away from moisture and incompatible substances to maintain stability. Our packaging options include 25 kg drums, with customization available to meet specific logistical requirements. Partner with us for reliable sourcing, competitive bulk pricing, and technical support tailored to your synthesis needs.