5-Chlorouracil
- CAS No.1820-81-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 5-Chlorouracil (CAS 1820-81-1) supplied for pharmaceutical synthesis and quality control reference. Reliable bulk availability with full documentation.
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Product Overview
5-Chlorouracil is a critical halogenated pyrimidine derivative widely recognized in the pharmaceutical and biochemical research sectors. As a specialized chemical intermediate, it serves as a fundamental building block for the synthesis of various antiviral and antineoplastic agents. Our facility produces this compound under strict quality management systems to ensure consistency and reliability for downstream manufacturing processes. The substance is characterized by its stable crystalline structure and high reactivity in nucleophilic substitution reactions, making it indispensable for medicinal chemistry applications.
We understand the stringent requirements of the global pharmaceutical supply chain. Therefore, our 5-Chlorouracil is manufactured with a focus on purity and trace impurity control. This product is particularly valuable for researchers developing fluoropyrimidine analogs or requiring precise reference standards for quality assurance protocols. By choosing our supply, partners gain access to a robust production capacity backed by decades of expertise in fine chemical synthesis.
Key Specifications
Quality is the cornerstone of our manufacturing process. Each batch undergoes rigorous analytical testing to confirm compliance with international standards. The physical and chemical properties are tightly controlled to ensure optimal performance in synthesis reactions. Below are the typical specifications for our commercial grade material:
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥99.0% |
| Loss on Drying | ≤1.0% |
| Melting Point | >300°C |
| Residue on Ignition | ≤0.10% |
| Heavy Metals | ≤10ppm |
The data above represents our standard quality control metrics. We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for that batch. This transparency allows our clients to validate the material against their internal protocols before integration into their production lines.
Industrial Applications
Primarily utilized as a pharmaceutical intermediate, 5-Chlorouracil plays a vital role in the development of therapeutic agents. It is commonly employed in the synthesis of nucleoside analogs used in experimental treatments for neoplastic conditions. Additionally, it serves as a key impurity reference standard, such as Fluorouracil EP Impurity E, aiding regulatory compliance for finished drug products. Laboratories also utilize this compound for biochemical research involving pyrimidine metabolism and enzyme inhibition studies.
- Synthesis of antiviral and anticancer active pharmaceutical ingredients (APIs).
- Reference standard for quality control in pharmaceutical manufacturing.
- Research tool for studying nucleic acid analogs and metabolic pathways.
- Custom synthesis projects requiring halogenated pyrimidine building blocks.
Quality Assurance and Logistics
Our commitment to excellence extends beyond production to packaging and storage. The product is packaged in 25 kg drums or according to specific customer requirements to maintain integrity during transit. We recommend storage in a cool, ventilated environment away from direct sunlight and moisture to preserve chemical stability. Our logistics team ensures timely global delivery, adhering to all relevant safety regulations for chemical transport. Partner with us for a reliable supply of 5-Chlorouracil that meets the demands of modern pharmaceutical innovation.
