Intermediates

5-Fluoro-2-iodotoluene

  • CAS No.28490-56-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Fluoro-2-iodotoluene (CAS 28490-56-4) designed for advanced organic synthesis and pharmaceutical intermediate manufacturing.

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Product Technical Details

Product Overview

5-Fluoro-2-iodotoluene is a specialized fluorinated aromatic intermediate essential for modern organic synthesis and pharmaceutical development. As a key building block, this compound facilitates the introduction of both fluorine and iodine functionalities into complex molecular structures. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for research and industrial scale applications.

This chemical serves as a critical precursor in the synthesis of various active pharmaceutical ingredients (APIs) and agrochemical compounds. The presence of the iodine atom allows for versatile cross-coupling reactions, such as Suzuki or Heck couplings, while the fluorine moiety enhances metabolic stability and bioavailability in final drug products. We adhere to strict quality control protocols to guarantee performance in sensitive synthetic routes.

Technical Specifications

ParameterValue
Product Name5-Fluoro-2-iodotoluene
CAS Number28490-56-4
Molecular FormulaC7H6FI
Molecular Weight236.03 g/mol
AppearanceBrown liquid
Purity≥98%
Water Content≤0.5%
Density1.788 g/cm3
Boiling Point206.8°C at 760 mmHg
Flash Point82.1°C

Industrial Applications

The primary utility of 5-Fluoro-2-iodotoluene lies in its role as a versatile intermediate for fine chemical synthesis. It is extensively used in the pharmaceutical industry for constructing fluorinated drug candidates. Additionally, it finds application in agrochemical research where fluorinated structures are required for enhanced pesticidal activity. The compound is also valuable in material science for developing specialized polymers and liquid crystals.

  • Pharmaceutical intermediate synthesis
  • Agrochemical active ingredient production
  • Organic cross-coupling reactions
  • Fluorinated polymer development
  • Research and development laboratories

Quality Assurance and Storage

Every batch of 5-Fluoro-2-iodotoluene undergoes rigorous testing using advanced analytical methods including GC and HPLC to confirm purity and identity. We provide a Certificate of Analysis (COA) with each shipment to ensure transparency and compliance with international standards. Proper storage is crucial to maintain product integrity over time.

Store this material in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed when not in use to prevent moisture absorption and oxidation. Always handle with appropriate personal protective equipment (PPE) including gloves and safety goggles. In case of spillage, follow standard chemical safety procedures for containment and disposal.

Why Choose Our Manufacturer

As a global manufacturer with decades of experience in fine chemicals, we offer competitive bulk pricing and reliable supply chain logistics. Our technical team provides support for customization and scale-up requirements. We are committed to delivering high-quality intermediates that meet the demanding specifications of the pharmaceutical and chemical industries worldwide.