5-Fluoro-2-methylaniline
- CAS No.367-29-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Fluoro-2-methylaniline (CAS 367-29-3), a versatile fluoroaromatic intermediate for pharmaceutical, agrochemical, and OLED material synthesis.
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Product Overview
5-Fluoro-2-methylaniline is a high-value fluoro-substituted aromatic amine widely employed as a key building block in advanced organic synthesis. With a molecular formula of C7H8FN and a molecular weight of 125.14, this compound features a strategically positioned fluorine atom and methyl group on the aniline ring, enabling selective functionalization in multi-step syntheses. It appears as a light yellow to brown solid with a melting point range of 38–40 °C and a boiling point of 98–100 °C at 15 mmHg.
Specifications
| Molecular Formula | C7H8FN |
|---|---|
| Molecular Weight | 125.14 g/mol |
| Purity | ≥98% |
| Water Content | ≤0.5% |
| Refractive Index | 1.538 |
| Flash Point | 194 °F |
| UN Number | UN2810 |
| Transport Hazard Class | 6.1 |
| Packing Group | III |
Industrial Applications
This fluoroaniline derivative serves primarily as a critical intermediate in the production of complex active pharmaceutical ingredients (APIs), specialty agrochemicals, high-performance dyes, and organic electronic materials such as those used in OLED technologies. Its electron-withdrawing fluorine substituent enhances reactivity and selectivity in electrophilic and nucleophilic aromatic substitution reactions, making it indispensable in fine chemical manufacturing.
- Enables regioselective synthesis in heterocyclic drug scaffolds
- Used in the development of novel crop protection agents
- Acts as a precursor for fluorinated azo dyes and pigments
- Supports R&D in emissive layers for next-generation displays
Handling and Storage
Store in a cool, dry, and well-ventilated area with the container tightly closed. Due to its classification as a Toxic Liquid, Organic, N.O.S. (UN2810, Class 6.1, Packing Group III), appropriate personal protective equipment and compliance with local hazardous material regulations are required during handling and transport.
