5-Fluoro-2-methylbenzaldehyde
- CAS No.22062-53-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Fluoro-2-methylbenzaldehyde (CAS 22062-53-9), a key fluorinated intermediate for advanced organic synthesis in pharmaceutical and agrochemical manufacturing.
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Product Overview
5-Fluoro-2-methylbenzaldehyde is a high-value fluorinated aromatic aldehyde widely employed as a critical building block in the synthesis of complex organic molecules. With its precisely positioned fluoro and methyl substituents on the benzene ring, this compound offers unique electronic and steric properties that enhance reactivity and selectivity in multi-step synthetic pathways. It is particularly valued in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals where fluorine incorporation improves metabolic stability, bioavailability, and target binding affinity.
Specifications
| Molecular Formula | C8H7FO |
|---|---|
| Molecular Weight | 138.14 g/mol |
| Appearance | Colorless to yellow transparent liquid |
| Purity (GC) | ≥99.0% |
| Density | 1.1446 g/cm³ |
| Boiling Point | 99°C |
| Flash Point | 77°C |
| Refractive Index | 1.5244 |
Industrial Applications
As a versatile synthetic intermediate, 5-Fluoro-2-methylbenzaldehyde serves as a foundational scaffold in medicinal chemistry and fine chemical production. Its primary applications include:
- Construction of heterocyclic cores in drug discovery programs targeting neurological and oncological pathways
- Synthesis of fluorinated analogs for structure-activity relationship (SAR) studies
- Preparation of ligands and catalysts in asymmetric synthesis
- Intermediate in the manufacture of high-performance agrochemicals requiring enhanced environmental persistence and efficacy
Manufactured under stringent quality control protocols, our product meets global regulatory standards for industrial use. Packaging is available in standard 200 kg drums or customized configurations upon request. Store in a cool, dry, and well-ventilated area away from ignition sources to maintain stability and performance.
