Intermediates

5-Fluoro-2-methylbenzonitrile

  • CAS No.77532-79-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Fluoro-2-methylbenzonitrile (CAS 77532-79-7) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate applications.

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Product Technical Details

Product Overview

5-Fluoro-2-methylbenzonitrile stands as a pivotal compound within the landscape of fine chemical synthesis and pharmaceutical development. As a fluorinated aromatic nitrile, this substance offers unique reactivity profiles that are essential for constructing complex molecular architectures. Our facility specializes in the production of this high-value intermediate, ensuring consistent quality and reliability for downstream processes. The presence of the fluoro substituent enhances metabolic stability and lipophilicity in final drug candidates, making this building block highly sought after in medicinal chemistry programs.

We understand the critical nature of supply chain stability for research and production teams. Therefore, our manufacturing protocols are designed to maintain strict batch-to-batch consistency. Whether utilized for scale-up activities or initial discovery phases, our 5-Fluoro-2-methylbenzonitrile meets the rigorous demands of modern chemical synthesis. We prioritize purity and structural integrity to minimize impurities that could affect subsequent reaction yields.

Key Specifications

ParameterSpecification
Chemical Name5-Fluoro-2-methylbenzonitrile
CAS Number77532-79-7
Molecular FormulaC8H6FN
Molecular Weight135.14 g/mol
Purity≥99.0%
Melting Point42-45°C
AppearanceOff-white crystalline powder
Flash Point79°C

Industrial Applications

This fluorinated nitrile serves as a versatile precursor in the synthesis of various active pharmaceutical ingredients (APIs). The nitrile group provides a handle for further functionalization, such as hydrolysis to carboxylic acids or reduction to amines, enabling diverse synthetic routes. Additionally, the compound finds utility in the agrochemical sector, where fluorinated structures are increasingly valued for their enhanced biological activity and environmental profiles.

Beyond pharmaceuticals and agrochemicals, this intermediate is applicable in material science research. Its stability and reactivity make it suitable for developing specialized polymers and organic electronic materials. Our technical team supports customers in identifying optimal synthesis routes, leveraging our deep understanding of fluorinated chemistry to improve process efficiency.

Quality Assurance and Storage

Quality control is paramount in our production process. Every batch of 5-Fluoro-2-methylbenzonitrile undergoes comprehensive analysis using advanced chromatographic and spectroscopic methods. We provide a Certificate of Analysis (COA) with each shipment, detailing purity levels and impurity profiles. This transparency ensures that our partners can maintain their own quality standards without compromise.

For optimal preservation, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper sealing is recommended to prevent degradation over extended periods. We offer flexible packaging options, including standard 25 kg drums or custom configurations based on specific logistical requirements. Our global distribution network ensures timely delivery while maintaining product integrity during transit.